Journal
JOURNAL OF CLINICAL MEDICINE
Volume 10, Issue 9, Pages -Publisher
MDPI
DOI: 10.3390/jcm10092007
Keywords
Prader-Willi Syndrome; awareness; insight; obesity; BMI; functionality
Categories
Funding
- Fondo de Investigacion Sanitaria del Instituto Carlos III
- Fondo Europeo de Desarrollo Regional [PI-18/0734]
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The study found that patients with Prader-Willi Syndrome (PWS) had good awareness of the illness and medication effects, but lacked awareness of the social consequences of the disease. They were well aware of obesity/overweight and excessive appetite, but only mildly aware of excessive food intake. Insight was correlated with age and functionality, but not with BMI. PWS patients showed better insight into the illness compared to schizophrenia-spectrum patients, but similar awareness of medication effects and social consequences.
There are no studies about insight or awareness of illness in patients with Prader-Willi Syndrome (PWS). The objective of this study was to explore the level of awareness of the disorder, of the need for medication, and of the social consequences of the disease, as well as of its main symptoms in PWS. We also aimed to explore relationships between awareness and sociodemographic and clinical characteristics, and to compare all data with a matched sample of patients with psychosis. Insight was assessed by an Adapted version of the Scale of Unawareness of Mental Disorder in a cross-sectional pilot study at a University Hospital. Thirty-six individuals with PWS (58.3% women) were included. Results showed that PWS patients had a good awareness of the illness and of the effects of medication, in contrast to a lack of awareness of illness' social consequences. Awareness of obesity/overweight was excellent, as was the awareness of excessive appetite. Awareness of excessive food intake was only mild. Insight correlated with age and functionality, but not with BMI. PWS patients showed a better insight into the illness but a similar awareness of the effects of the medication and of the social consequences of the disease as compared to schizophrenia-spectrum patients. This profile of insight may have relevant clinical implications.
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