Journal
FRONTIERS IN ENDOCRINOLOGY
Volume 12, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fendo.2021.556851
Keywords
contrast enhanced ultrasound; papillary thyroid carcinoma; conventional ultrasound; Hashimoto’ s thyroiditis; central lymph node metastasis (CLNM)
Categories
Funding
- National Natural Science Foundation of China [81974267]
- Hunan Provincial Natural Science Foundation of China [2018JJ2575]
- Hunan Provincial Health Commission Research Foundation Project [B2019166]
Ask authors/readers for more resources
This study evaluated the sonographic characteristics of papillary thyroid carcinoma (PTC) with Hashimoto's thyroiditis (HT) and found that factors like patient age, nodule size, shape, calcification, and vascularity were associated with central lymph node metastasis (CLNM). Preoperative ultrasound characteristics can help predict CLNM in PTCs with coexistent HT.
The purpose of this study was to evaluate the usefulness of the sonographic characteristics of papillary thyroid carcinoma (PTC) with Hashimoto's thyroiditis (HT) for predicting central lymph node metastasis (CLNM). One hundred thirty-three patients who underwent thyroidectomy and central cervical lymph node dissection for PTC with coexistent HT were retrospectively analyzed. All PTCs with HT were preoperatively evaluated by ultrasound (US) regarding their nodular number, size, component, shape, margin, echogenicity, calcification, capsule contact with protrusion, vascularity and contrast enhanced ultrasound (CEUS) parameters. Univariate analysis demonstrated that patients with PTCs with HT and CLNM more frequently had age <= 45 years, size > 10 mm, a wider than tall shape, microcalcification, hypo-enhancement and peak intensity index < 1 than those without CLNM (all p<0.05). Binary logistic regression analysis demonstrated that size > 10 mm and CEUS hypo-enhancement were independent characteristics for the presence of CLNM. Our study indicated that preoperative US characteristics could offer help in predicting CLNM in PTCs with coexistent HT.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available