4.6 Article

Pneumonia

Journal

NATURE REVIEWS DISEASE PRIMERS
Volume 7, Issue 1, Pages -

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41572-021-00259-0

Keywords

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Funding

  1. ICREA award from Generalitat de Catalunya
  2. SEPAR fellowship 2018
  3. Fondo de Investigacion Sanitaria [PI19/00207]
  4. SEPAR fellowship Programa Mentor

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Pneumonia is a common acute respiratory infection that affects individuals of all ages globally, causing high morbidity and mortality. It can be caused by various microorganisms, and timely identification of causative pathogens is crucial for effective treatment. New therapies and diagnostic tests are being developed to improve the management of pneumonia.
Pneumonia is a common acute respiratory infection that affects the alveoli and distal airways; it is a major health problem and associated with high morbidity and short-term and long-term mortality in all age groups worldwide. Pneumonia is broadly divided into community-acquired pneumonia or hospital-acquired pneumonia. A large variety of microorganisms can cause pneumonia, including bacteria, respiratory viruses and fungi, and there are great geographical variations in their prevalence. Pneumonia occurs more commonly in susceptible individuals, including children of <5 years of age and older adults with prior chronic conditions. Development of the disease largely depends on the host immune response, with pathogen characteristics having a less prominent role. Individuals with pneumonia often present with respiratory and systemic symptoms, and diagnosis is based on both clinical presentation and radiological findings. It is crucial to identify the causative pathogens, as delayed and inadequate antimicrobial therapy can lead to poor outcomes. New antibiotic and non-antibiotic therapies, in addition to rapid and accurate diagnostic tests that can detect pathogens and antibiotic resistance will improve the management of pneumonia. Pneumonia is a respiratory infection of the distal airways; it can be acquired in the community or in the hospital, and it can be caused by several types of bacteria, viruses, fungi and other pathogens.

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