4.8 Review

The Immunology of Hormone Receptor Positive Breast Cancer

Related references

Note: Only part of the references are listed.
Review Immunology

Macrophage Biology and Mechanisms of Immune Suppression in Breast Cancer

Anita K. Mehta et al.

Summary: Macrophages play a significant role in breast cancer progression, with their infiltration associated with poor prognosis. Tumor-associated macrophages impede productive tumor immunity by limiting antigen presentation and supporting tumor cell survival, angiogenesis, and metastasis, highlighting the urgent need to overcome their immune suppression for durable anti-tumor immunity in breast cancer.

FRONTIERS IN IMMUNOLOGY (2021)

Article Oncology

Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer

Anita K. Mehta et al.

Summary: The study reveals that PARP inhibition affects macrophage metabolism and function in BRCA-associated TNBC, and combining PARP inhibition with CSF1R blockade therapy enhances antitumor immunity and prolongs survival. Targeting macrophage-mediated immune suppression can improve the efficacy of PARP inhibitors.

NATURE CANCER (2021)

Article Oncology

Immune Checkpoint Profiles in Luminal B Breast Cancer (Alliance)

Meenakshi Anurag et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2020)

Article Oncology

Unraveling Triple-Negative Breast Cancer Tumor Microenvironment Heterogeneity: Towards an Optimized Treatment Approach

Yacine Bareche et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2020)

Review Oncology

The Ongoing Search for Biomarkers of CDK4/6 Inhibitor Responsiveness in Breast Cancer

Scott F. Schoninger et al.

MOLECULAR CANCER THERAPEUTICS (2020)

Article Multidisciplinary Sciences

B cells are associated with survival and immunotherapy response in sarcoma

Florent Petitprez et al.

NATURE (2020)

Article Multidisciplinary Sciences

Tertiary lymphoid structures improve immunotherapy and survival in melanoma

Rita Cabrita et al.

NATURE (2020)

Article Multidisciplinary Sciences

The single-cell pathology landscape of breast cancer

Hartland W. Jackson et al.

NATURE (2020)

Article Multidisciplinary Sciences

B cells and tertiary lymphoid structures promote immunotherapy response

Beth A. Helmink et al.

NATURE (2020)

Review Biotechnology & Applied Microbiology

NK cells for cancer immunotherapy

Noriko Shimasaki et al.

NATURE REVIEWS DRUG DISCOVERY (2020)

Article Medicine, General & Internal

Pembrolizumab for Early Triple-Negative Breast Cancer

Peter Schmid et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Medicine, Research & Experimental

Multiplexed ion beam imaging (MIBI) for characterization of the tumor microenvironment across tumor types

Jason Ptacek et al.

LABORATORY INVESTIGATION (2020)

Review Oncology

Tim-3 finds its place in the cancer immunotherapy landscape

Nandini Acharya et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020)

Review Oncology

TIGIT in cancer immunotherapy

Joe-Marc Chauvin et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020)

Article Biochemical Research Methods

Robust Cell Detection and Segmentation for Image Cytometry Reveal Th17 Cell Heterogeneity

Takahiro Tsujikawa et al.

CYTOMETRY PART A (2019)

Article Medicine, Research & Experimental

Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers

Tina Gruosso et al.

JOURNAL OF CLINICAL INVESTIGATION (2019)

Article Multidisciplinary Sciences

Infiltration of CD8+ T cells into tumor cell clusters in triple-negative breast cancer

Xuefei Li et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Review Medicine, General & Internal

Recent advances in triple negative breast cancer: the immunotherapy era

Antonio Marra et al.

BMC MEDICINE (2019)

Article Biochemistry & Molecular Biology

A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer

Johanna Wagner et al.

Article Oncology

Breast cancer statistics, 2019

Carol E. DeSantis et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2019)

Article Oncology

The prognostic significance of peritumoral tertiary lymphoid structures in breast cancer

Michael Sofopoulos et al.

CANCER IMMUNOLOGY IMMUNOTHERAPY (2019)

Article Biochemistry & Molecular Biology

Antiestrogens in combination with immune checkpoint inhibitors in breast cancer immunotherapy

Diana C. Marquez-Garban et al.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2019)

Article Multidisciplinary Sciences

Clinicopathological values of PD-L1 expression in HER2-positive breast cancer

Sasagu Kurozumi et al.

SCIENTIFIC REPORTS (2019)

Review Oncology

The evolving landscape of biomarkers for checkpoint inhibitor immunotherapy

Jonathan J. Havel et al.

NATURE REVIEWS CANCER (2019)

Article Oncology

Clinical Implications of Tumor-Infiltrating Immune Cells in Breast Cancer

Shi-Chao Zhang et al.

JOURNAL OF CANCER (2019)

Article Biochemistry & Molecular Biology

Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment

Elham Azizi et al.

Article Immunology

The Immune Landscape of Cancer

Vesteinn Thorsson et al.

IMMUNITY (2018)

Review Immunology

Immune checkpoint blockade therapy for cancer: An overview of FDA-approved immune checkpoint inhibitors

Kristian M. Hargadon et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2018)

Review Oncology

Breast Cancer Biology: Clinical Implications for Breast Radiation Therapy

Janet K. Horton et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2018)

Review Biochemistry & Molecular Biology

Understanding the tumor immune microenvironment (TIME) for effective therapy

Mikhail Binnewies et al.

NATURE MEDICINE (2018)

Article Biochemistry & Molecular Biology

Enhancer mapping uncovers phenotypic heterogeneity and evolution in patients with luminal breast cancer

Darren K. Patten et al.

NATURE MEDICINE (2018)

Article Multidisciplinary Sciences

Quantitative mass imaging of single biological macromolecules

Gavin Young et al.

SCIENCE (2018)

Article Oncology

A Comprehensive Immunologic Portrait of Triple-Negative Breast Cancer

Zhixian Liu et al.

TRANSLATIONAL ONCOLOGY (2018)

Review Biochemistry & Molecular Biology

Macrophages: The Road Less Traveled, Changing Anticancer Therapy

Jennifer L. Guerriero

TRENDS IN MOLECULAR MEDICINE (2018)

Article Oncology

Immunological differences between primary and metastatic breast cancer

B. Szekely et al.

ANNALS OF ONCOLOGY (2018)

Review Oncology

Multiple modes of action of eribulin mesylate: Emerging data and clinical implications

Javier Cortes et al.

CANCER TREATMENT REVIEWS (2018)

Article Biochemistry & Molecular Biology

Deep Profiling of Mouse Splenic Architecture with CODEX Multiplexed Imaging

Yury Goltsev et al.

Article Pharmacology & Pharmacy

Talazoparib: First Global Approval

Sheridan M. Hoy

DRUGS (2018)

Article Medicine, General & Internal

Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer

P. Schmid et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Review Oncology

Relevance of Tumor-Infiltrating Immune Cell Composition and Functionality for Disease Outcome in Breast Cancer

Rico D. Bense et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2017)

Review Oncology

Relevance of Tumor-Infiltrating Immune Cell Composition and Functionality for Disease Outcome in Breast Cancer

Rico D. Bense et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2017)

Article Oncology

MONARCH 3: Abemaciclib As Initial Therapy for Advanced Breast Cancer

Matthew P. Goetz et al.

JOURNAL OF CLINICAL ONCOLOGY (2017)

Article Multidisciplinary Sciences

CDK4/6 inhibition triggers anti-tumour immunity

Shom Goel et al.

NATURE (2017)

Review Multidisciplinary Sciences

PARP inhibitors: Synthetic lethality in the clinic

Christopher J. Lord et al.

SCIENCE (2017)

Article Multidisciplinary Sciences

A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer

Paola A. Betancur et al.

NATURE COMMUNICATIONS (2017)

Article Multidisciplinary Sciences

Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer

Woosung Chung et al.

NATURE COMMUNICATIONS (2017)

Review Biochemistry & Molecular Biology

Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy

Padmanee Sharma et al.

Review Oncology

Clinical relevance of host immunity in breast cancer: from TILs to the clinic

Peter Savas et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2016)

Article Pathology

The immune microenvironment of breast ductal carcinoma in situ

Elizabeth Thompson et al.

MODERN PATHOLOGY (2016)

Review Immunology

IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance

David H. Munn et al.

TRENDS IN IMMUNOLOGY (2016)

Review Oncology

Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy

Suzanne L. Topalian et al.

NATURE REVIEWS CANCER (2016)

Review Oncology

The biology and function of fibroblasts in cancer

Raghu Kalluri

NATURE REVIEWS CANCER (2016)

Editorial Material Biochemistry & Molecular Biology

CD47 blockade as another immune checkpoint therapy for cancer

Robert H. Vonderheide

NATURE MEDICINE (2015)

Article Biochemical Research Methods

Robust enumeration of cell subsets from tissue expression profiles

Aaron M. Newman et al.

NATURE METHODS (2015)

Article Multidisciplinary Sciences

HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells

Huimin Zhang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Oncology

Prognostic and predictive value of PDL1 expression in breast cancer

Renaud Sabatier et al.

ONCOTARGET (2015)

Article Biotechnology & Applied Microbiology

Selective Inhibition of Tumor Growth by Clonal NK Cells Expressing an ErbB2/HER2-Specific Chimeric Antigen Receptor

Kurt Schönfeld et al.

MOLECULAR THERAPY (2014)

Article Biochemical Research Methods

Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry

Charlotte Giesen et al.

NATURE METHODS (2014)

Review Immunology

Tertiary lymphoid structures in cancer and beyond

Marie-Caroline Dieu-Nosjean et al.

TRENDS IN IMMUNOLOGY (2014)

Article Oncology

PD-L1 Expression in Triple-Negative Breast Cancer

Elizabeth A. Mittendorf et al.

CANCER IMMUNOLOGY RESEARCH (2014)

Article Medicine, Research & Experimental

CD4+ follicular helper T cell infiltration predicts breast cancer survival

Chunyan Gu-Trantien et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Review Oncology

MHC Class I Antigen Processing and Presenting Machinery: Organization, Function, and Defects in Tumor Cells

Patrizia Leone et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2013)

Article Multidisciplinary Sciences

Mutational heterogeneity in cancer and the search for new cancer-associated genes

Michael S. Lawrence et al.

NATURE (2013)

Article Multidisciplinary Sciences

Mutational landscape and significance across 12 major cancer types

Cyriac Kandoth et al.

NATURE (2013)

Article Oncology

Inflammatory cells in node-negative breast cancer

Britta Lofdahl et al.

ACTA ONCOLOGICA (2012)

Article Oncology

Mechanistic analysis of the antitumor efficacy of human natural killer cells against breast cancer cells

Keiko Kajitani et al.

BREAST CANCER RESEARCH AND TREATMENT (2012)

Article Pathology

Tumour-infiltrating macrophages and clinical outcome in breast cancer

S. M. A. Mahmoud et al.

JOURNAL OF CLINICAL PATHOLOGY (2012)

Article Multidisciplinary Sciences

Leukocyte composition of human breast cancer

Brian Ruffell et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Oncology

The blockade of immune checkpoints in cancer immunotherapy

Drew M. Pardoll

NATURE REVIEWS CANCER (2012)

Article Oncology

Clinical implication of HLA class I expression in breast cancer

Koichi Kaneko et al.

BMC CANCER (2011)

Review Biochemistry & Molecular Biology

Macrophage Diversity Enhances Tumor Progression and Metastasis

Bin-Zhi Qian et al.

Article Medicine, Research & Experimental

Chemotherapy enhances tumor cell susceptibility to CTL-mediated killing during cancer immunotherapy in mice

Rupal Ramakrishnan et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Biochemistry & Molecular Biology

A CD8+ T cell transcription signature predicts prognosis in autoimmune disease

Eoin F. McKinney et al.

NATURE MEDICINE (2010)

Article Biochemistry & Molecular Biology

CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis

Siddhartha Jaiswal et al.

Review Cell Biology

Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation

G. Solinas et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2009)

Article Immunology

Treg suppressive activity involves estrogen-dependent expression of programmed death-1 (PD-1)

Magdalena J. Polanczyk et al.

INTERNATIONAL IMMUNOLOGY (2007)

Article Biotechnology & Applied Microbiology

An immune response gene expression module identifies a good prognosis subtype in estrogen receptor negative breast cancer

Andrew E. Teschendorff et al.

GENOME BIOLOGY (2007)

Review Biochemistry & Molecular Biology

Macrophages: Obligate partners for tumor cell migration, invasion, and metastasis

J Condeelis et al.

Article Oncology

Total loss of MHC class I is an independent indicator of good prognosis in breast cancer

Z Madjd et al.

INTERNATIONAL JOURNAL OF CANCER (2005)

Article Immunology

Negative regulation of T cell homeostasisby lymphocyte activation gene-3 (CD223)

CJ Workman et al.

JOURNAL OF IMMUNOLOGY (2005)

Article Oncology

Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated

S Demaria et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2004)

Article Biochemistry & Molecular Biology

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

R Edgar et al.

NUCLEIC ACIDS RESEARCH (2002)