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CD4+ T-Cell Help in the Tumor Milieu Is Required for Recruitment and Cytolytic Function of CD8+ T Lymphocytes
Rinke Bos et al.
CANCER RESEARCH (2010)
Tumor cells disseminate early, but immunosurveillance limits metastatic outgrowth, in a mouse model of melanoma
Jo Eyles et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Th Cells Act Via Two Synergistic Pathways To Promote Antiviral CD8+ T Cell Responses
Melanie Wiesel et al.
JOURNAL OF IMMUNOLOGY (2010)
HER3 overexpression in breast cancer conveys a poor prognosis
Lisa Richards
Nature Reviews Clinical Oncology (2010)
Poor survival outcomes in HER2-positive breast cancer patients with low-grade, node-negative tumours
S. M. Tovey et al.
BRITISH JOURNAL OF CANCER (2009)
Quantitative Multiplexed Analysis of ErbB Family Coexpression for Primary Breast Cancer Prognosis in a Large Retrospective Cohort
Jennifer M. Giltnane et al.
CANCER (2009)
The CD4+ T-Cell Response of Melanoma Patients to a MAGE-A3 Peptide Vaccine Involves Potential Regulatory T Cells
Violaine Francois et al.
CANCER RESEARCH (2009)
HER2 overexpression correlates with survival after curative resection of pancreatic cancer
Masahiro Komoto et al.
CANCER SCIENCE (2009)
Gene Regulation and Chromatin Remodeling by IL-12 and Type I IFN in Programming for CD8 T Cell Effector Function and Memory
Pujya Agarwal et al.
JOURNAL OF IMMUNOLOGY (2009)
Ki67 Index, HER2 Status, and Prognosis of Patients With Luminal B Breast Cancer
Maggie C. U. Cheang et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2009)
HER2 in gastric cancer: a new prognostic factor and a novel therapeutic target
C. Gravalos et al.
ANNALS OF ONCOLOGY (2008)
Therapy of advanced established murine breast cancer with a recombinant adenoviral ErbB-2/neu vaccine
Jong Myun Park et al.
CANCER RESEARCH (2008)
Endogenous Interleukin-4 Promotes Tumor Development by increasing Tumor Cell Resistance to Apoptosis
Zhiguang Li et al.
CANCER RESEARCH (2008)
TRAIL deficiency does not rescue impaired CD8+ T cell memory generated in the absence of CD4+ T cell help
Jilian A. Sacks et al.
JOURNAL OF IMMUNOLOGY (2008)
Cancer-related inflammation
Alberto Mantovani et al.
NATURE (2008)
IL-15 as a mediator of CD4(+) help for CD8(+) T cell longevity and avoidance of TRAIL-mediated apoptosis
SangKon Oh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Batf3 Deficiency Reveals a Critical Role for CD8α+ Dendritic Cells in Cytotoxic T Cell Immunity
Kai Hildner et al.
SCIENCE (2008)
Elements related to heterogeneity of antibody-dependent cell cytotoxicity in patients under trastuzumab therapy for primary operable breast cancer overexpressing Her2
Stefania Varchetta et al.
CANCER RESEARCH (2007)
CD4 T cells are required for CD8 T cell survival during both primary and memory recall responses
Patricia Novy et al.
JOURNAL OF IMMUNOLOGY (2007)
Adaptive immunity maintains occult cancer in an equilibrium state
Catherine M. Koebel et al.
NATURE (2007)
CD4+ CD25+ Foxp3+ regulatory T cells induce cytokine deprivation -mediated apoptosis of effector CD4+ T cells
Pushpa Pandiyan et al.
NATURE IMMUNOLOGY (2007)
Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells
Eva V. Acosta-Rodriguez et al.
NATURE IMMUNOLOGY (2007)
Human CD4+ T cells lyse target cells via Granzyme/Perforin upon circumvention of MHU class II restriction by an antibody-like immunoreceptor
Andreas Hombach et al.
JOURNAL OF IMMUNOLOGY (2006)
Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4 T cell-dendritic cell interaction
F Castellino et al.
NATURE (2006)
Differential expression of inflammatory chemokines by Th1- and Th2-cell promoting dendritic cells: A role for different mature dendritic cell populations in attracting appropriate effector cells to peripheral sites of inflammation
MC Lebre et al.
IMMUNOLOGY AND CELL BIOLOGY (2005)
Early role of CD4+ Th1 cells and antibodies in HER-2 adenovirus vaccine protection against autochthonous mammary carcinomas
JM Park et al.
JOURNAL OF IMMUNOLOGY (2005)
Dendritic cell-mediated T cell polarization
EC de Jong et al.
SPRINGER SEMINARS IN IMMUNOPATHOLOGY (2005)
Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-β signals in vivoi
ML Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
IL-12 enhances the generation of tumour antigen-specific Th1CD4 T cells during ex vivo expansion
KL Knutson et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2004)
Rapid high efficiency sensitization of CD8+ T cells to tumor antigens by dendritic cells leads to enhanced functional avidity and direct tumor recognition through an IL-12-dependent mechanism
SW Xu et al.
JOURNAL OF IMMUNOLOGY (2003)
Similarities and differences in CD4+ and CD8+ effector and memory T cell generation
RA Seder et al.
NATURE IMMUNOLOGY (2003)
Survey of naturally occurring CD4+ T cell responses against NY-ESO-1 in cancer patients:: Correlation with antibody responses
S Gnjatic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Requirement for CD4 T cell help in generating functional CD8 T cell memory
DJ Shedlock et al.
SCIENCE (2003)
CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes
EM Janssen et al.
NATURE (2003)
Calcium signaling inhibits interleukin-12 production and activates CD83+ dendritic cells that induce Th2 cell development
MB Faries et al.
BLOOD (2001)
Immunologic self-tolerance maintained by CD25+CD4+ regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
T Takahashi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Granule exocytosis, and not the Fas/Fas ligand system, is the main pathway of cytotoxicity mediated by alloantigen-specific CD4+ as well as CD8+ cytotoxic T lymphocytes in humans
M Yasukawa et al.
BLOOD (2000)