Journal
BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 51, Issue 2, Pages 429-437Publisher
UNIV SAO PAULO, CONJUNTO QUIMICAS
DOI: 10.1590/S1984-82502015000200020
Keywords
Norfloxacin/determination; Graphene oxide; Nafion; Voltammetry/differential pulse; Pharmaceutical formulations/quantitative analysis
Categories
Funding
- National Natural Science Foundation of China [81370869]
Ask authors/readers for more resources
In this approach, a new voltammetric method for determination of norfloxacin was proposed with high sensitivity and wider detection linear range. The used voltammetric sensor was fabricated simply by coating a layer of graphene oxide (GO) and Nafion composited film on glassy carbon electrode. The advantage of proposed method was sensitive electrochemical response for norfloxacin, which was attributed to the excellent electrical conductivity of GO and the accumulating function of Nafion under optimum experimental conditions, the present method revealed a good linear response for determination of norfloxacin in the range of 1x10(-8) mol/L-7x10(-6) mol/L with a detection limit of 5x10(-9) mol/L. The proposed method was successfully applied in the determination of norfloxacin in capsules with satisfactory results.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available