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Macrophage PTEN Regulates Expression and Secretion of Arginase I Modulating Innate and Adaptive Immune Responses
Emine Sahin et al.
JOURNAL OF IMMUNOLOGY (2014)
A Macrophage-Dominant PI3K Isoform Controls Hypoxia-Induced HIF1α and HIF2α Stability and Tumor Growth, Angiogenesis, and Metastasis
Shweta Joshi et al.
MOLECULAR CANCER RESEARCH (2014)
Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis
Laura Bonapace et al.
NATURE (2014)
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
Oscar R. Colegio et al.
NATURE (2014)
Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities
Erin D. Lew et al.
ELIFE (2014)
A phase II trial of dasatinib in patients with metastatic castration-resistant prostate cancer treated previously with chemotherapy
Przemyslaw W. Twardowski et al.
ANTI-CANCER DRUGS (2013)
Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes
Daigo Hashimoto et al.
IMMUNITY (2013)
Possible anti-tumor activity of initial treatment with zoledronic acid with hormonal therapy for bone-metastatic prostate cancer in multicenter clinical trial
Hiroji Uemura et al.
INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY (2013)
MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis
Rebecca S. Cook et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
High efficacy of CpG-ODN, Cetuximab and Cisplatin combination for very advanced ovarian xenograft tumors
Michele Sommariva et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2013)
CSF-1R inhibition alters macrophage polarization and blocks glioma progression
Stephanie M. Pyonteck et al.
NATURE MEDICINE (2013)
Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response
Diane Tseng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production
Alessandro Michelucci et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Up-Regulation of PD-L1, IDO, and Tregs in the Melanoma Tumor Microenvironment Is Driven by CD8+ T Cells
Stefani Spranger et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Macrophage M1/M2 Polarization Dynamically Adapts to Changes in Cytokine Microenvironments in Cryptococcus neoformans Infection
Michael J. Davis et al.
MBIO (2013)
The TSC-mTOR pathway regulates macrophage polarization
Vanessa Byles et al.
NATURE COMMUNICATIONS (2013)
Fate of TLR-1/TLR-2 agonist functionalised pDNA nanoparticles upon deposition at the human bronchial epithelium in vitro
Simon Heuking et al.
JOURNAL OF NANOBIOTECHNOLOGY (2013)
Recent advances reveal IL-8 signaling as a potential key to targeting breast cancer stem cells
Jagdeep K. Singh et al.
BREAST CANCER RESEARCH (2013)
Randomized clinical trial of imiquimod: an adjunct to treating cervical dysplasia
Deirdre R. Pachman et al.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2012)
Small interfering RNA targeting HMGN5 induces apoptosis via modulation of a mitochondrial pathway and Bcl-2 family proteins in prostate cancer cells
Xiao-Yu Zhang et al.
ASIAN JOURNAL OF ANDROLOGY (2012)
Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors
Anne-Katrine Bonde et al.
BMC CANCER (2012)
TNF-α Mediates Macrophage-Induced Bystander Effects through Netrin-1
Yonghong Yang et al.
CANCER RESEARCH (2012)
Impact of the small molecule Met inhibitor BMS-777607 on the metastatic process in a rodent tumor model with constitutive c-Met activation
Yao Dai et al.
CLINICAL & EXPERIMENTAL METASTASIS (2012)
Topical TLR7 Agonist Imiquimod Can Induce Immune-Mediated Rejection of Skin Metastases in Patients with Breast Cancer
Sylvia Adams et al.
CLINICAL CANCER RESEARCH (2012)
Activation of Natural Killer T Cells Promotes M2 Macrophage Polarization in Adipose Tissue and Improves Systemic Glucose Tolerance via Interleukin-4 (IL-4)/STAT6 Protein Signaling Axis in Obesity
Yewei Ji et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Phase I study of the anti-CD40 humanized monoclonal antibody lucatumumab (HCD122) in relapsed chronic lymphocytic leukemia
John C. Byrd et al.
LEUKEMIA & LYMPHOMA (2012)
Differential Macrophage Activation Alters the Expression Profile of NTPDase and Ecto-5′-Nucleotidase
Rafael Fernandes Zanin et al.
PLOS ONE (2012)
A Cell Permeable Peptide Inhibitor of NFAT Inhibits Macrophage Cytokine Expression and Ameliorates Experimental Colitis
Houda Z. Elloumi et al.
PLOS ONE (2012)
Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization
Alicia Arranz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
IDO inhibits a tryptophan sufficiency signal that stimulates mTOR A novel IDO effector pathway targeted by D-1-methyl-tryptophan
Richard Metz et al.
ONCOIMMUNOLOGY (2012)
Expression patterns of the immunomodulatory enzyme arginase 1 in blood, lymph nodes and tumor tissue of early-stage breast cancer patients
Jana de Boniface et al.
ONCOIMMUNOLOGY (2012)
Immunogenic cell death and DAMPs in cancer therapy
Dmitri V. Krysko et al.
NATURE REVIEWS CANCER (2012)
Dasatinib as a Single Agent in Triple-Negative Breast Cancer: Results of an Open-Label Phase 2 Study
Richard S. Finn et al.
CLINICAL CANCER RESEARCH (2011)
Inflammation and wound healing: the role of the macrophage
Timothy J. Koh et al.
EXPERT REVIEWS IN MOLECULAR MEDICINE (2011)
COMPLETE RESTORATION OF REFRACTORY MANDIBULAR OSTEORADIONECROSIS BY PROLONGED TREATMENT WITH A PENTOXIFYLLINE-TOCOPHEROL-CLODRONATE COMBINATION (PENTOCLO): A PHASE II TRIAL
Sylvie Delanian et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2011)
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
Bin-Zhi Qian et al.
NATURE (2011)
Amelioration of sepsis by inhibiting sialidase-mediated disruption of the CD24-SiglecG interaction
Guo-Yun Chen et al.
NATURE BIOTECHNOLOGY (2011)
Nilotinib: A Novel, Selective Tyrosine Kinase Inhibitor
Jean-Yves Blay et al.
SEMINARS IN ONCOLOGY (2011)
The redox protein HMGB1 regulates cell death and survival in cancer treatment
Daolin Tang et al.
AUTOPHAGY (2010)
Epithelial cell-directed efferocytosis in the post-partum mammary gland is necessary for tissue homeostasis and future lactation
Melissa Sandahl et al.
BMC DEVELOPMENTAL BIOLOGY (2010)
R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
Sacha J. Holland et al.
CANCER RESEARCH (2010)
Fra-1 protooncogene regulates IL-6 expression in macrophages and promotes the generation of M2d macrophages
Qingshan Wang et al.
CELL RESEARCH (2010)
Tubby and tubby-like protein 1 are new MerTK ligands for phagocytosis
Nora B. Caberoy et al.
EMBO JOURNAL (2010)
The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
Takashi Satoh et al.
NATURE IMMUNOLOGY (2010)
Introduction to metallic nanoparticles
Vicky V. Mody et al.
JOURNAL OF PHARMACY AND BIOALLIED SCIENCES (2010)
Lung environment determines unique phenotype of alveolar macrophages
Amanda M. Guth et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2009)
Chemotherapy induces ATP release from tumor cells
Isabelle Martins et al.
CELL CYCLE (2009)
CD24 and Siglec-10 Selectively Repress Tissue Damage-Induced Immune Responses
Guo-Yun Chen et al.
SCIENCE (2009)
An exploratory study of systemic administration of the Toll-like receptor-7 agonist 852A in patients with refractory metastatic melanoma
Reinhard Dummer et al.
CLINICAL CANCER RESEARCH (2008)
Inhibition of self engulfment through deactivation of myosin-II at the phagocytic synapse between human cells
Richard K. Tsai et al.
JOURNAL OF CELL BIOLOGY (2008)
Colony-stimulating factors in inflammation and autoimmunity
John A. Hamilton
NATURE REVIEWS IMMUNOLOGY (2008)
TAM receptors are pleiotropic inhibitors of the innate immune response
Carla V. Rothlin et al.
CELL (2007)
First in human phase I trial of 852A, a novel systemic toll-like receptor 7 agionist, to activate innate immune responses in patients with advanced cancer
Arkadiusz Z. Dudek et al.
CLINICAL CANCER RESEARCH (2007)
High mobility group box I (HMGB1) release from tumor cells after treatment: Implications for development of targeted chemoimmunotherapy
Xiang Da (Eric) Dong et al.
JOURNAL OF IMMUNOTHERAPY (2007)
Phase 1, pharmacokinetic (PK) and pharmacodynamic (PD) study of oral alvespimycin (A; KOS-1022; 17-DMAG): Two different schedules in patients with advanced malignancies
K. T. Flaherty et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Meta-analysis of clodronate and breast cancer survival
T. C. Ha et al.
BRITISH JOURNAL OF CANCER (2007)
Clinical activity and immune modulation in cancer patients treated with CP-870,893, a novel CD40 agonist monoclonal antibody
Robert H. Vonderheide et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Inhibition of indoleamine 2,3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with antitumor responses
De-Yan Hou et al.
CANCER RESEARCH (2007)
The extracellular release of HMGB1 during apoptotic cell death
Charles W. Bell et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: New molecules and patterns of gene expression
Fernando O. Martinez et al.
JOURNAL OF IMMUNOLOGY (2006)
Clodronate-liposome-mediated depletion of tumour-associated macrophages:: a new and highly effective antiangiogenic therapy approach
S. M. Zeisberger et al.
BRITISH JOURNAL OF CANCER (2006)
Efficacy and safety of zoledronic acid in patients with breast cancer metastatic to bone: A multicenter clinical trial
Giacomo Carteni et al.
ONCOLOGIST (2006)
Development of real-time subcellular dynamic multicolor imaging of cancer-cell trafficking in live mice with a variable-magnification whole-mouse imaging system
K Yamauchi et al.
CANCER RESEARCH (2006)
Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-γ- and CD40L-mediated costimulation
Frank A. W. Verreck et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2006)
Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte
SJ Gardai et al.
CELL (2005)
Effect of inflammation on cyclooxygenase (COX)-2 expression in benign and malignant oesophageal cells
SI Abdalla et al.
CARCINOGENESIS (2005)
Evodiamine abolishes constitutive and inducible NF-κB activation by inhibiting IκBα kinase activation, thereby suppressing NF-κB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion
Y Takada et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2, macrophages subvert, immunity to (myco)bacteria
FAW Verreck et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
CD47 mediates killing of breast tumor cells via Gi-dependent inhibition of protein kinase A
PP Manna et al.
CANCER RESEARCH (2004)
Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses
PC Rodriguez et al.
CANCER RESEARCH (2004)
CpG oligodeoxynucleotide enhances tumor response to radiation
L Milas et al.
CANCER RESEARCH (2004)
The chemokine system in diverse forms of macrophage activation and polarization
A Mantovani et al.
TRENDS IN IMMUNOLOGY (2004)
A novel mechanism for TNF-α regulation by p38 MAPK:: Involvement of NF-κB with implications for therapy in rheumatoid arthritis
J Campbell et al.
JOURNAL OF IMMUNOLOGY (2004)
Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities
J Vollmer et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2004)
The three Es of cancer immunoediting
GP Dunn et al.
ANNUAL REVIEW OF IMMUNOLOGY (2004)
Induction of heat shock proteins (HSPs) by sodium arsenite in cultured astrocytes and reduction of hydrogen peroxide-induced cell death
B Fauconneau et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Tumor-associated macrophages express lymphatic endothelial growth factors and are related to peritumoral lymphangiogenesis
SF Schoppmann et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Mer receptor tyrosine kinase signaling.: Prevention of apoptosis and alteration of cytoskeletal architecture without stimulation or proliferation.
KL Guttridge et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
p38 mitogen-activated protein kinase is activated and linked to TNF-α signaling in inflammatory bowel disease
GH Waetzig et al.
JOURNAL OF IMMUNOLOGY (2002)
Human macrophage activation programs induced by bacterial pathogens
GJ Nau et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Positive regulatory role of IL-12 in macrophages and modulation by IFN-γ
U Grohmann et al.
JOURNAL OF IMMUNOLOGY (2001)
IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity
V Shankaran et al.
NATURE (2001)
Distinct modes of macrophage recognition for apoptotic and necrotic cells are not specified exclusively by phosphatidylserine exposure
RE Cocco et al.
MOLECULAR BIOLOGY OF THE CELL (2001)
M-1/M-2 macrophages and the Th1/Th2 paradigm
CD Mills et al.
JOURNAL OF IMMUNOLOGY (2000)