4.8 Review

The Fate of Activated Group 2 Innate Lymphoid Cells

Related references

Note: Only part of the references are listed.
Article Immunology

Induction of IL-10-producing type 2 innate lymphoid cells by allergen immunotherapy is associated with clinical response

Korneliusz Golebski et al.

Summary: IL-10(+) ILC2s play a crucial role in modulating grass-pollen allergy, attenuating Th responses, and maintaining epithelial cell integrity. Patients with grass-pollen allergy have lower levels of IL-10(+) KLRG1(+) ILC2s, but this ability to produce IL-10 is restored after immunotherapy treatment. The mechanisms underlying this involve modifications in retinol metabolic pathway, cytokine-cytokine receptor interaction, and JAK-STAT signaling pathways in the ILCs.

IMMUNITY (2021)

Article Immunology

Steroid-resistant human inflammatory ILC2s are marked by CD45RO and elevated in type 2 respiratory diseases

Esmee K. van der Ploeg et al.

Summary: Human CD45RO(+) inflammatory ILC2s, identified as an analog of mouse iILC2s, are associated with severe type 2 inflammatory disease and therapy resistance. Activation of these ILC2s is tightly linked to epithelial alarmins, leading to their increase in inflamed mucosal tissue.

SCIENCE IMMUNOLOGY (2021)

Article Immunology

ILC2s are the predominant source of intestinal ILC-derived IL-10

Jennifer K. Bando et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2020)

Article Immunology

Tissue-specific pathways extrude activated ILC2s to disseminate type 2 immunity

Roberto R. Ricardo-Gonzalez et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2020)

Article Cell Biology

Innate Lymphoid Cells Play a Pathogenic Role in Pericarditis

Hee Sun Choi et al.

CELL REPORTS (2020)

Article Immunology

Adventitial Stromal Cells Define Group 2 Innate Lymphoid Cell Tissue Niches

Madelene W. Dahlgren et al.

IMMUNITY (2019)

Article Allergy

Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid

Hideaki Morita et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2019)

Article Immunology

CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer

Laura M. McLane et al.

Annual Review of Immunology (2019)

Article Critical Care Medicine

Elevated Levels of Type 2 Respiratory Innate Lymphoid Cells in Human Infants with Severe Respiratory Syncytial Virus Bronchiolitis

Luan D. Vu et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2019)

Article Multidisciplinary Sciences

IL-1β, IL-23, and TGF-β drive plasticity of human ILC2s towards IL-17-producing ILCs in nasal inflammation

Korneliusz Golebski et al.

NATURE COMMUNICATIONS (2019)

Article Immunology

Non-cytotoxic Cardiac Innate Lymphoid Cells Are a Resident and Quiescent Type 2-Commited Population

William Bracamonte-Baran et al.

FRONTIERS IN IMMUNOLOGY (2019)

Article Allergy

Neonatal hyperoxia promotes asthma-like features through IL-33-dependent ILC2 responses

In Su Cheon et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2018)

Article Cell Biology

Interleukin 17 Family Cytokines: Signaling Mechanisms, Biological Activities, and Therapeutic Implications

Leticia Monin et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2018)

Article Biochemistry & Molecular Biology

A Metabolite-Triggered Tuft Cell-ILC2 Circuit Drives Small Intestinal Remodeling

Christoph Schneider et al.

Review Immunology

ILC2 memory: Recollection of previous activation

Itziar Martinez-Gonzalez et al.

IMMUNOLOGICAL REVIEWS (2018)

Review Biochemistry & Molecular Biology

Innate Lymphoid Cells: 10 Years On

Eric Vivier et al.

Article Immunology

Tissue signals imprint ILC2 identity with anticipatory function

Roberto R. Ricardo-Gonzalez et al.

NATURE IMMUNOLOGY (2018)

Review Immunology

Social Networking of Group Two Innate Lymphoid Cells in Allergy and Asthma

Benjamin P. Hurrell et al.

FRONTIERS IN IMMUNOLOGY (2018)

Letter Allergy

Group 2 innate lymphoid cell activation in the neonatal lung drives type 2 immunity and allergen sensitization

Catherine A. Steer et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2017)

Article Immunology

ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control

Christian Schwartz et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2017)

Review Immunology

Alarmins: Feel the Stress

Peleg Rider et al.

JOURNAL OF IMMUNOLOGY (2017)

Review Immunology

Immunological Memory of Group 2 Innate Lymphoid Cells

Itziar Martinez-Gonzalez et al.

TRENDS IN IMMUNOLOGY (2017)

Article Multidisciplinary Sciences

Alternative activation generates IL-10 producing type 2 innate lymphoid cells

Corey R. Seehus et al.

NATURE COMMUNICATIONS (2017)

Article Cell Biology

First-Breath-Induced Type 2 Pathways Shape the Lung Immune Environment

Simona Saluzzo et al.

CELL REPORTS (2017)

Article Immunology

Group 2 Innate Lymphoid Cells Exhibit a Dynamic Phenotype in Allergic Airway Inflammation

Bobby W. S. Li et al.

FRONTIERS IN IMMUNOLOGY (2017)

Article Immunology

Group 2 innate lymphoid cells are elevated and activated in chronic rhinosinusitis with nasal polyps

Julie A. Poposki et al.

IMMUNITY INFLAMMATION AND DISEASE (2017)

Article Critical Care Medicine

Mucosal Type 2 Innate Lymphoid Cells Are a Key Component of the Allergic Response to Aeroallergens

Jaideep Dhariwal et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2017)

Article Multidisciplinary Sciences

Tuft-cell-derived IL-25 regulates an intestinal ILC2-epithelial response circuit

Jakob von Moltke et al.

NATURE (2016)

Article Critical Care Medicine

Prostaglandin I2 Signaling and Inhibition of Group 2 Innate Lymphoid Cell Responses

Weisong Zhou et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2016)

Article Immunology

IL-12 drives functional plasticity of human group 2 innate lymphoid cells

Ai Ing Lim et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2016)

Article Biochemistry & Molecular Biology

Activated Type 2 Innate Lymphoid Cells Regulate Beige Fat Biogenesis

Min-Woo Lee et al.

Review Biochemistry & Molecular Biology

IL-4 and IL-13 signaling in allergic airway disease

Naina Gour et al.

CYTOKINE (2015)

Article Allergy

Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33

Christina A. Christianson et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2015)

Article Immunology

Innate immunological function of TH2 cells in vivo

Liying Guo et al.

NATURE IMMUNOLOGY (2015)

Article Multidisciplinary Sciences

Tissue residency of innate lymphoid cells in lymphoid and nonlymphoid organs

Georg Gasteiger et al.

SCIENCE (2015)

Article Multidisciplinary Sciences

Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity

Jonathan R. Brestoff et al.

NATURE (2015)

Article Allergy

Enhanced innate type 2 immune response in peripheral blood from patients with asthma

Kathleen R. Bartemes et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2014)

Article Allergy

Group 2 innate lymphoid cells facilitate sensitization to local, but not systemic, TH2-einducing allergen exposures

Matthew J. Gold et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2014)

Article Multidisciplinary Sciences

IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis

Emily Hams et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Critical Care Medicine

IL-33-Responsive Innate Lymphoid Cells Are an Important Source of IL-13 in Chronic Rhinosinusitis with Nasal Polyps

Joanne L. Shaw et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2013)

Article Immunology

Interleukin-33-Dependent Innate Lymphoid Cells Mediate Hepatic Fibrosis

Tamar Mchedlidze et al.

IMMUNITY (2013)

Article Immunology

A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis

Maryam Salimi et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2013)

Article Immunology

Critical Role of p38 and GATA3 in Natural Helper Cell Function

Jun-ichi Furusawa et al.

JOURNAL OF IMMUNOLOGY (2013)

Article Cell Biology

TSLP Elicits IL-33-Independent Innate Lymphoid Cell Responses to Promote Skin Inflammation

Brian S. Kim et al.

SCIENCE TRANSLATIONAL MEDICINE (2013)

Article Immunology

Innate lymphoid cells - a proposal for uniform nomenclature

Hergen Spits et al.

NATURE REVIEWS IMMUNOLOGY (2013)

Article Physiology

STAT6 regulates natural helper cell proliferation during lung inflammation initiated by Alternaria

Taylor A. Doherty et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2012)

Article Hematology

Cytokine activation induces human memory-like NK cells

Rizwan Romee et al.

BLOOD (2012)

Article Immunology

Pulmonary innate lymphoid cells are major producers of IL-5 and IL-13 in murine models of allergic asthma

Roel G. J. Klein Wolterink et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2012)

Article Allergy

Innate IL-13-producing nuocytes arise during allergic lung inflammation and contribute to airways hyperreactivity

Jillian L. Barlow et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2012)

Article Critical Care Medicine

IL-9 Governs Allergen-induced Mast Cell Numbers in the Lung and Chronic Remodeling of the Airways

Jennifer Kearley et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)

Article Immunology

Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

Laurel A. Monticelli et al.

NATURE IMMUNOLOGY (2011)

Article Multidisciplinary Sciences

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

Daniel R. Neill et al.

NATURE (2010)

Article Multidisciplinary Sciences

Systemically dispersed innate IL-13-expressing cells in type 2 immunity

April E. Price et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Thymic stromal lymphopoietin-mediated STAT5 phosphorylation via kinases JAK1 and JAK2 reveals a key difference from IL-7-induced signaling

Yrina Rochman et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Immunology

IL-5-and eosinophil-mediated inflammation: from discovery to therapy

Taku Kouro et al.

INTERNATIONAL IMMUNOLOGY (2009)

Article Immunology

TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis

Betsy C. Taylor et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2009)

Correction Multidisciplinary Sciences

Adaptive immune features of natural killer cells (vol 457, pg 557, 2009)

Joseph C. Sun et al.

NATURE (2009)

Article Biochemistry & Molecular Biology

House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

Hamida Hammad et al.

NATURE MEDICINE (2009)

Article Multidisciplinary Sciences

Cytokine-induced memory-like natural killer cells

Megan A. Cooper et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells

Liying Guo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo

Virginie Carriere et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Biochemistry & Molecular Biology

Interleukin-25 and interieukin-13 production by alveolar macrophages in response to particles

CM Kang et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2005)