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CpG-ODN-induced sustained expression of BTLA mediating selective inhibition of human B cells
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B and T lymphocyte attenuator inhibits LPS-induced endotoxic shock by suppressing Toll-like receptor 4 signaling in innate immune cells
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CD8+ T Cells Specific for Tumor Antigens Can Be Rendered Dysfunctional by the Tumor Microenvironment through Upregulation of the Inhibitory Receptors BTLA and PD-1
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BTLA expression contributes to septic morbidity and mortality by inducing innate inflammatory cell dysfunction
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Monoclonal antibodies to B and T lymphocyte attenuator (BTLA) have no effect on in vitro B cell proliferation and act to inhibit in vitro T cell proliferation when presented in a cis, but not trans, format relative to the activating stimulus
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Lack of B and T lymphocyte attenuator exacerbates autoimmune disorders and induces Fas-independent liver injury in MRL-lpr/lpr mice
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B and T Lymphocyte Attenuator Restricts the Protective Immune Response against Experimental Malaria
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Regulation of inflammation, autoimmunity, and infection immunity by HVEM-BTLA signaling
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Association of BTLA gene polymorphisms with the risk of malignant breast cancer in Chinese women of Heilongjiang Province
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Targeting of B and T lymphocyte associated (BTLA) prevents graft-versus-host disease without global immunosuppression
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B and T Lymphocyte Attenuator Suppresses IL-21 Production from Follicular Th Cells and Subsequent Humoral Immune Responses
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INTERNATIONAL JOURNAL OF IMMUNOGENETICS (2009)
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JOURNAL OF IMMUNOLOGY (2009)
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JOURNAL OF IMMUNOLOGY (2009)
Cutting Edge: A Critical Role of B and T Lymphocyte Attenuator in Peripheral T Cell Tolerance Induction
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JOURNAL OF IMMUNOLOGY (2009)
B and T Lymphocyte Attenuator Tempers Early Infection Immunity
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JOURNAL OF IMMUNOLOGY (2009)
T Cell Intrinsic Heterodimeric Complexes between HVEM and BTLA Determine Receptivity to the Surrounding Microenvironment
Timothy C. Cheung et al.
JOURNAL OF IMMUNOLOGY (2009)
BTLA targeting modulates lymphocyte phenotype, function, and numbers and attenuates disease in nonobese diabetic mice
Wayne Truong et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2009)
Development of autoimmune hepatitis-like disease and production of autoantibodies to nuclear antigens in mice lacking B and T lymphocyte attenuator
Yoshihiro Oya et al.
ARTHRITIS AND RHEUMATISM (2008)
A crucial role for HVEM and BTLA in preventing intestinal inflammation
Marcos W. Steinberg et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
B and T lymphocyte attenuator regulates T cell survival in the lung
Christine Deppong et al.
JOURNAL OF IMMUNOLOGY (2008)
CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator
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NATURE IMMUNOLOGY (2008)
The inhibitory HVEM-BTLA pathway counter regulates lymphotoxin beta receptor signaling to achieve homeostasis of dendritic cells
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JOURNAL OF IMMUNOLOGY (2008)
Combined coinhibitory and costimulatory modulation with Anti-BTLA and CTLA4Ig facilitates tolerance in murine islet allografts
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AMERICAN JOURNAL OF TRANSPLANTATION (2007)
Negative and positive co-signaling with anti-BTLA (PJ196) and CTLA4Ig prolongs islet allograft survival
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TRANSPLANTATION (2007)
Ligation of B and T lymphocyte attenuator prevents the genesis of experimental cerebral malarial
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JOURNAL OF IMMUNOLOGY (2007)
Distinct expression and inhibitory function of B and T lymphocyte attenuator on human T cells
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Association of a BTLA gene polymorphism with the risk of rheumatoid arthritis
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Association of Grb-2 and PI3K p85 with phosphotyrosile peptides derived from BTLA
Maya Gavrieli et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Expression and function of the B and T lymphocyte attenuator (BTLA/CD272) on human T cells
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Cutting edge: B and T lymphocyte attenuator and programmed death receptor-1 inhibitory receptors are required for termination of acute allergic airway inflammation
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JOURNAL OF IMMUNOLOGY (2006)
B and T lymphocyte attenuator-mediated signal transduction provides a potent inhibitory signal to primary human CD4 T cells that can be initiated by multiple phosphotyrosine motifs
Jens M. Chemnitz et al.
JOURNAL OF IMMUNOLOGY (2006)
Balancing co-stimulation and inhibition with BTLA and HVEM
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NATURE REVIEWS IMMUNOLOGY (2006)
Attenuating lymphocyte activity - The crystal structure of the BTLA-HVEM complex
DM Compaan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Functional analysis of B and T lymphocyte attenuator engagement on CD4+ and CD8+ T cells
C Krieg et al.
JOURNAL OF IMMUNOLOGY (2005)
Differential effects of B and T lymphocyte attenutator and programmed death-1 on acceptance of partially versus fully MHC-mismatched cardiac allografts
R Tao et al.
JOURNAL OF IMMUNOLOGY (2005)
B and T lymphocyte attenuator exhibits structural and expression polymorphisms and is highly induced in anergic CD4+ T cells
MA Hurchla et al.
JOURNAL OF IMMUNOLOGY (2005)
A coreceptor interaction between the CD28 and TNF receptor family members B and T lymphocyte attenuator and herpesvirus entry mediator
LC Gonzalez et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator
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NATURE IMMUNOLOGY (2005)
An inhibitory Ig superfamily protein expressed by lymphocytes and APCs is also an early marker of thymocyte positive selection
P Han et al.
JOURNAL OF IMMUNOLOGY (2004)
Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of B and T lymphocyte attenuator required for association with protein tyrosine phosphatases SHP-1 and SHP-2
M Gavrieli et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1
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