4.7 Article

Chronic Sulfasalazine Treatment in Mice Induces System xc --Independent Adverse Effects

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

Cystine-glutamate antiporterxCTas a therapeutic target for cancer

Lin Liu et al.

Summary: xCT, a component of the cystine/glutamic acid reverse transporter, protects cells from oxidative stress and ferroptosis by promoting cystine uptake and glutathione biosynthesis. Its high expression in various tumors makes it a potential target for cancer treatment.

CELL BIOCHEMISTRY AND FUNCTION (2021)

Article Biochemistry & Molecular Biology

System Xc- Antiporter Inhibitors: Azo-Linked Amino-Naphthyl-Sulfonate Analogues of Sulfasalazine

M. Nehser et al.

NEUROCHEMICAL RESEARCH (2020)

Article Chemistry, Medicinal

Novel analogs of sulfasalazine as system xc- antiporter inhibitors: Insights from the molecular modeling studies

Dhavalkumar Patel et al.

DRUG DEVELOPMENT RESEARCH (2019)

Article Biochemistry & Molecular Biology

The possible ameliorative effect of simvastatin versus sulfasalazine on acetic acid induced ulcerative colitis in adult rats

N. A. Soliman et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2019)

Review Clinical Neurology

Excitotoxicity in the pathogenesis of neurological and psychiatric disorders: Therapeutic implications

Jordi Olloquequi et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2018)

Article Biotechnology & Applied Microbiology

Comparative Evaluation between Sulfasalazine Alone and in Combination with Herbal Medicine on DSS-Induced Ulcerative Colitis Mice

Mi-Rae Shin et al.

BIOMED RESEARCH INTERNATIONAL (2017)

Article Neurosciences

Cystine/Glutamate Antiporter Blockage Induces Myelin Degeneration

Federico N. Soria et al.

Article Immunology

Inhibition of System Xc- Transporter Attenuates Autoimmune Inflammatory Demyelination

Kirsten S. Evonuk et al.

JOURNAL OF IMMUNOLOGY (2015)

Article Clinical Neurology

Absence of system xc- in mice decreases anxiety and depressive-like behavior without affecting sensorimotor function or spatial vision

Eduard Bentea et al.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2015)

Article Neurosciences

Behavioral assessment of acute inhibition of system xc - in rats

Victoria Lutgen et al.

PSYCHOPHARMACOLOGY (2014)

Review Biochemistry & Molecular Biology

The Cystine/Glutamate Antiporter System xc- in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities

Jan Lewerenz et al.

ANTIOXIDANTS & REDOX SIGNALING (2013)

Review Pharmacology & Pharmacy

Excitotoxicity: Bridge to various triggers in neurodegenerative disorders

Ankita Mehta et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2013)

Article Endocrinology & Metabolism

Effects of Chronic Restraint Stress on Body Weight, Food Intake, and Hypothalamic Gene Expressions in Mice

Joo Yeon Jeong et al.

ENDOCRINOLOGY AND METABOLISM (2013)

Review Pathology

Pathology of Demyelinating Diseases

Bogdan F. Gh. Popescu et al.

ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 7 (2012)

Editorial Material Pharmacology & Pharmacy

Sulfasalazine for brain cancer fits

Harald Sontheimer et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2012)

Article Gastroenterology & Hepatology

Pharmacologic Evaluation of Sulfasalazine, FTY720, and Anti-IL-12/23p40 in a TNBS-Induced Crohn's Disease Model

Zaher A. Radi et al.

DIGESTIVE DISEASES AND SCIENCES (2011)

Article Clinical Neurology

Suppression of experimental autoimmune encephalomyelitis by sulfasalazine

M. Prosiegel et al.

ACTA NEUROLOGICA SCANDINAVICA (2010)

Article Endocrinology & Metabolism

Effects of Acute and Chronic Stressors and CRF in Rat and Mouse Tests for Depression

Adrian J. Dunn et al.

STRESS, NEUROTRANSMITTERS, AND HORMONES: NEUROENDOCRINE AND GENETIC MECHANISMS (2008)

Article Endocrinology & Metabolism

Sulfasalazine-induced cystine starvation: Potential use for prostate cancer therapy

Daniel W. Doxsee et al.

PROSTATE (2007)

Review Behavioral Sciences

A hitchhiker's guide to behavioral analysis in laboratory rodents

N Sousa et al.

GENES BRAIN AND BEHAVIOR (2006)

Article Biochemistry & Molecular Biology

Redox imbalance in cystine/glutamate transporter-deficient mice

H Sato et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Multidisciplinary Sciences

Slc7a11 gene controls production of pheomelanin pigment and proliferation of cultured cells

S Chintala et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Pharmacology & Pharmacy

The novel neuroprotective action of sulfasalazine through blockade of NMDA receptors

BR Ryu et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)

Article Physiology

Weight loss in rats exposed to repeated acute restraint stress is independent of energy or leptin status

RBS Harris et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2002)