Journal
CURRENT CARDIOLOGY REPORTS
Volume 23, Issue 6, Pages -Publisher
SPRINGER
DOI: 10.1007/s11886-021-01495-2
Keywords
Loneliness; Cardiovascular disease; Epidemiology; Health policy; Health promotion
Categories
Funding
- MARCH Mental Health Network - Cross-Disciplinary Mental Health Network Plus initiative - UK Research and Innovation [ES/S002588/1]
- Wellcome Trust [205407/Z/16/Z]
- ESRC [ES/T006994/1]
- Leverhulme Trust [PLP-2018-007]
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Loneliness is associated with an increased risk of early mortality and cardiovascular disease, similar to well-known risk factors like obesity and smoking. This association is likely mediated by health-related behaviors, biological mechanisms, and psychological factors that can negatively impact health.
Purpose of review In this review, we synthesise recent research on the association between loneliness and cardiovascular disease (CVD). We present evidence for mechanisms underlying this association and propose directions for future research. Recent findings Loneliness is related to increased risk of early mortality and CVD comparable to other well-established risk factors such as obesity or smoking. Loneliness has been linked to higher rates of incident CVD, poorer CVD patient outcomes, and early mortality from CVD. Loneliness likely affects risk for these outcomes via health-related behaviours (e.g. physical inactivity and smoking), biological mechanisms (e.g. inflammation, stress reactivity), and psychological factors (e.g. depression) to indirectly damage health.
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