Journal
JOURNAL OF NANOBIOTECHNOLOGY
Volume 19, Issue 1, Pages -Publisher
BMC
DOI: 10.1186/s12951-021-00870-z
Keywords
Second near-infrared (NIR-11) window; Fluorescence imaging; Biomedical applications
Funding
- National Key Research and Development Projects intergovernmental cooperation in science and technology of China [2018YFE0126900]
- National Natural Science Foundation of China [82072026, 81901852]
- China Postdoctoral Science Foundation [2020M681902]
- Postdoctoral Foundation of ZheJiang province [ZJ2020034]
- Fundamental Research Funds for the Central Universities
- Postdoctoral Foundation of ZheJiang province
Ask authors/readers for more resources
NIR imaging technology, especially NIR-II, has promising applications in biomedicine due to its advantages such as low autofluorescence, high signal-to-noise ratio, and high tissue penetration depth. This technology is a heavily researched topic and holds great potential for future applications in various biological tissues.
Molecular imaging technology enables us to observe the physiological or pathological processes in living tissue at the molecular level to accurately diagnose diseases at an early stage. Optical imaging can be employed to achieve the dynamic monitoring of tissue and pathological processes and has promising applications in biomedicine. The traditional first near-infrared (NIR-I) window (NIR-I, range from 700 to 900 nm) imaging technique has been available for more than two decades and has been extensively utilized in clinical diagnosis, treatment and scientific research. Compared with NIR-I, the second NIR window optical imaging (NIR-II, range from 1000 to 1700 nm) technology has low autofluorescence, a high signal-to-noise ratio, a high tissue penetration depth and a large Stokes shift. Recently, this technology has attracted significant attention and has also become a heavily researched topic in biomedicine. In this study, the optical characteristics of different fluorescence nanoprobes and the latest reports regarding the application of NIR-II nanoprobes in different biological tissues will be described. Furthermore, the existing problems and future application perspectives of NIR-II optical imaging probes will also be discussed.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available