Journal
FRONTIERS IN MICROBIOLOGY
Volume 12, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fmicb.2021.519836
Keywords
microbiome transplant; poop; microbiome; FMT; fecal
Categories
Funding
- External Industry Grant (Biotek Abadi) [GBA-808138, GBA-808813]
- Microbiome and Bioresource Research Strength (MBRS), Jeffrey Cheah School of Medicine and Health Sciences [MBRS/JCSMHS/02/2020]
- External Industry Grant (Biomerge) [BMRG2018-01]
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Fecal microbiome transplant (FMT) has shown success in treating gastrointestinal diseases by resolving gut microbiome dysbiosis through the administration of fecal materials from healthy donors. Imbalance in gut microbiota has been linked to infections and the development of common diseases.
Fecal microbiome transplant (FMT) has gained popularity over the past few years, given its success in treating several gastrointestinal diseases. At the same time, microbial populations in the gut have been shown to have more physiological effects than we expected as habitants of the gut. The imbalance in the gut microbiome or dysbiosis, particularly when there are excessive harmful pathogens, can trigger not just infections but can also result in the development of common diseases, such as cancer and cardiometabolic diseases. By using FMT technology, the dysbiosis of the gut microbiome in patients can be resolved by administering fecal materials from a healthy donor. The current review summarizes the history and current uses of FMT before suggesting potential ideas for its high-quality application in clinical settings.
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