4.7 Review

Role and Mechanism of Gut Microbiota in Human Disease

Related references

Note: Only part of the references are listed.
Article Biotechnology & Applied Microbiology

A unified catalog of 204,938 reference genomes from the human gut microbiome

Alexandre Almeida et al.

Summary: The Unified Human Gastrointestinal Genome (UHGG) and Protein (UHGP) collections include a large number of non-redundant genomes and protein sequences, which are crucial for studying the relationship between genotypes and phenotypes in the human gut microbiome.

NATURE BIOTECHNOLOGY (2021)

Review Microbiology

Gut microbiota in human metabolic health and disease

Yong Fan et al.

Summary: The intestinal microbiota plays a significant role in human metabolic health, potentially contributing to the development of common metabolic disorders when dysregulated. Current research is shifting towards cause-and-effect studies and utilizing high-throughput human multi-omics data to identify potential molecular mechanisms behind these associations.

NATURE REVIEWS MICROBIOLOGY (2021)

Review Microbiology

The gut microbiota-brain axis in behaviour and brain disorders

Livia H. Morais et al.

Summary: This Review discusses the intricate and potentially important connections between the gut microbiota and the brain, involving bidirectional communication along the gut-brain axis. Emerging evidence suggests that disruptions in microbial communities may be implicated in neurological disorders, with animal models providing valuable insights into the pathways linking the gut and the brain which could have tangible impacts on human health.

NATURE REVIEWS MICROBIOLOGY (2021)

Review Nutrition & Dietetics

Gut microbiota-associated trimethylamine N-oxide and increased cardiometabolic risk in adults: a systematic review and dose-response meta-analysis

Mahdieh Abbasalizad Farhangi et al.

Summary: The meta-analysis found a positive association between circulating TMAO levels and increased risk of hypertension and other cardiometabolic disorders in adults. High TMAO concentrations were also associated with changes in blood pressure and lipid levels.

NUTRITION REVIEWS (2021)

Review Clinical Neurology

Implications of the Gut Microbiome in Parkinson's Disease

Mohamed Elfil et al.

MOVEMENT DISORDERS (2020)

Review Gastroenterology & Hepatology

Gut microbiota-derived metabolites as key actors in inflammatory bowel disease

Aonghus Lavelle et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2020)

Review Pharmacology & Pharmacy

Gut microbiota and neuroinflammation in pathogenesis of hypertension: A potential role for hydrogen sulfide

Basak Donertas Ayaz et al.

PHARMACOLOGICAL RESEARCH (2020)

Article Biochemistry & Molecular Biology

A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors

Ina Nemet et al.

Article Multidisciplinary Sciences

Implication of the gut microbiome composition of type 2 diabetic patients from northern China

Qian Li et al.

SCIENTIFIC REPORTS (2020)

Review Immunology

Gut Microbiota and Gestational Diabetes Mellitus: A Review of Host-Gut Microbiota Interactions and Their Therapeutic Potential

Zubaidah Hasain et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2020)

Review Endocrinology & Metabolism

Evaluating the Causal Role of Gut Microbiota in Type 1 Diabetes and Its Possible Pathogenic Mechanisms

He Zhou et al.

FRONTIERS IN ENDOCRINOLOGY (2020)

Review Medicine, General & Internal

A Role for Gut Microbiome Fermentative Pathways in Fatty Liver Disease Progression

Paula Iruzubieta et al.

JOURNAL OF CLINICAL MEDICINE (2020)

Article Multidisciplinary Sciences

Microbiota-derived metabolite promotes HDAC3 activity in the gut

Shu-en Wu et al.

NATURE (2020)

Article Multidisciplinary Sciences

The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic

Eliran Kadosh et al.

NATURE (2020)

Review Gastroenterology & Hepatology

Intestinal permeability in human nonalcoholic fatty liver disease: A systematic review and meta-analysis

Toon J. I. De Munck et al.

LIVER INTERNATIONAL (2020)

Article Multidisciplinary Sciences

Microbiota-modulated CART+ enteric neurons autonomously regulate blood glucose

Paul A. Muller et al.

SCIENCE (2020)

Review Endocrinology & Metabolism

Prevention of Gestational Diabetes Mellitus (GDM) and Probiotics: Mechanism of Action: A Review

Aziz Homayouni et al.

CURRENT DIABETES REVIEWS (2020)

Review Immunology

Host-microbiota interactions in inflammatory bowel disease

Roberta Caruso et al.

NATURE REVIEWS IMMUNOLOGY (2020)

Article Peripheral Vascular Disease

Potential Influences of Gut Microbiota on the Formation of Intracranial Aneurysm

Fumiaki Shikata et al.

HYPERTENSION (2019)

Review Food Science & Technology

Revisit gut microbiota and its impact on human health and disease

Rui-xue Ding et al.

JOURNAL OF FOOD AND DRUG ANALYSIS (2019)

Review Gastroenterology & Hepatology

Effect of ethanol on lipid metabolism

Min You et al.

JOURNAL OF HEPATOLOGY (2019)

Editorial Material Multidisciplinary Sciences

The gut microbiota and colon cancer

Wendy S. Garrett

SCIENCE (2019)

Article Neurosciences

Gut Microbiota Differs Between Parkinson's Disease Patients and Healthy Controls in Northeast China

Chunxiao Li et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2019)

Article Clinical Neurology

Mild cognitive impairment has similar alterations as Alzheimer's disease in gut microbiota

Binyin Li et al.

ALZHEIMERS & DEMENTIA (2019)

Review Endocrinology & Metabolism

The Genetic Contribution to Type 1 Diabetes

Marina Bakay et al.

CURRENT DIABETES REPORTS (2019)

Review Biochemistry & Molecular Biology

Microbial Metabolites Determine Host Health and the Status of Some Diseases

Panida Sittipo et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Endocrinology & Metabolism

Gut microbial metabolites in obesity, NAFLD and T2DM

Emanuel E. Canfora et al.

NATURE REVIEWS ENDOCRINOLOGY (2019)

Article Immunology

Alteration of the fecal microbiota in Chinese patients with Parkinson's disease

Yiwei Qian et al.

BRAIN BEHAVIOR AND IMMUNITY (2018)

Article Biochemistry & Molecular Biology

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women

Lesley Hoyles et al.

NATURE MEDICINE (2018)

Article Clinical Neurology

Gut microbiota in patients with Parkinson's disease in southern China

Aiqun Lin et al.

PARKINSONISM & RELATED DISORDERS (2018)

Article Multidisciplinary Sciences

SCFAs strongly stimulate PYY production in human enteroendocrine cells

P. Larraufie et al.

SCIENTIFIC REPORTS (2018)

Article Multidisciplinary Sciences

Gut microbiota is associated with obesity and cardiometabolic disease in a population in the midst of Westernization

Jacobo de la Cuesta-Zuluaga et al.

SCIENTIFIC REPORTS (2018)

Review Cardiac & Cardiovascular Systems

Role of gut microbiota in atherosclerosis

Annika Lindskog Jonsson et al.

NATURE REVIEWS CARDIOLOGY (2017)

Article Biochemistry & Molecular Biology

Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention

Ruixin Liu et al.

NATURE MEDICINE (2017)

Article Multidisciplinary Sciences

The gut microbiome in atherosclerotic cardiovascular disease

Zhuye Jie et al.

NATURE COMMUNICATIONS (2017)

Article Immunology

Alterations of the Gut Microbiome in Hypertension

Qiulong Yan et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2017)

Article Multidisciplinary Sciences

Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota

T. Harach et al.

SCIENTIFIC REPORTS (2017)

Article Neurosciences

Gut microbiota in Parkinson disease in a northern German cohort

Franziska Hopfner et al.

BRAIN RESEARCH (2017)

Review Peripheral Vascular Disease

Obstructive Sleep Apnea-Induced Hypertension: Role of the Gut Microbiota

David J. Durgan

CURRENT HYPERTENSION REPORTS (2017)

Review Peripheral Vascular Disease

Antihypertensive Effects of Probiotics

Inaki Robles-Vera et al.

CURRENT HYPERTENSION REPORTS (2017)

Review Biochemistry & Molecular Biology

Neuro-Immune Interactions at Barrier Surfaces

Henrique Veiga-Fernandes et al.

Article Biochemistry & Molecular Biology

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease

Timothy R. Sampson et al.

Article Biochemistry & Molecular Biology

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

Weifei Zhu et al.

Article Multidisciplinary Sciences

Persistent microbiome alterations modulate the rate of post-dieting weight regain

Christoph A. Thaiss et al.

NATURE (2016)

Review Cell Biology

Interaction of Hydrogen Sulfide with Nitric Oxide in the Cardiovascular System

B. V. Nagpure et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)

Article Cardiac & Cardiovascular Systems

Gut Microbiota Promote Angiotensin II-Induced Arterial Hypertension and Vascular Dysfunction

Susanne H. Karbach et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2016)

Article Biochemistry & Molecular Biology

Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

Jessica M. Yano et al.

Article Peripheral Vascular Disease

Gut Dysbiosis Is Linked to Hypertension

Tao Yang et al.

HYPERTENSION (2015)

Article Multidisciplinary Sciences

Microbiota and host determinants of behavioural phenotype in maternally separated mice

G. De Palma et al.

NATURE COMMUNICATIONS (2015)

Review Pharmacology & Pharmacy

Emerging role of hydrogen sulfide in hypertension and related cardiovascular diseases

Guoliang Meng et al.

BRITISH JOURNAL OF PHARMACOLOGY (2015)

Article Clinical Neurology

Gut Microbiota Are Related to Parkinson's Disease and Clinical Phenotype

Filip Scheperjans et al.

MOVEMENT DISORDERS (2015)

Article Gastroenterology & Hepatology

Fecal Microbiome and Volatile Organic Compound Metabolome in Obese Humans With Nonalcoholic Fatty Liver Disease

Maitreyi Raman et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2013)

Article Biochemistry & Molecular Biology

Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis

Robert A. Koeth et al.

NATURE MEDICINE (2013)

Review Microbiology

The interplay between the intestinal microbiota and the brain

Stephen M. Collins et al.

NATURE REVIEWS MICROBIOLOGY (2012)

Article Multidisciplinary Sciences

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

Zeneng Wang et al.

NATURE (2011)

Article Neurosciences

The H1 Haplotype of the Tau Gene (MAPT) is Associated with Mild Cognitive Impairment

Emilio Di Maria et al.

JOURNAL OF ALZHEIMERS DISEASE (2010)

Review Biochemistry & Molecular Biology

Molecular Pathology of Lewy Body Diseases

Katrin Beyer et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2009)

Article Cell Biology

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

Peter J. Turnbaugh et al.

SCIENCE TRANSLATIONAL MEDICINE (2009)

Article Multidisciplinary Sciences

An obesity-associated gut microbiome with increased capacity for energy harvest

Peter J. Turnbaugh et al.

NATURE (2006)

Letter Hematology

Human atherosclerotic plaque contains viable invasive Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis

EV Kozarov et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2005)