Related references
Note: Only part of the references are listed.Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms
Jean-Christophe Beltra et al.
IMMUNITY (2020)
The KMT2D Kabuki syndrome histone methylase controls neural crest cell differentiation and facial morphology
Karl B. Shpargel et al.
DEVELOPMENT (2020)
CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer
Laura M. McLane et al.
Annual Review of Immunology (2019)
Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection
Chen Yao et al.
NATURE IMMUNOLOGY (2019)
CUT&Tag for efficient epigenomic profiling of small samples and single cells
Hatice S. Kaya-Okur et al.
NATURE COMMUNICATIONS (2019)
Histone H3K27 Demethylase Negatively Controls the Memory Formation of Antigen-Stimulated CD8+ T Cells
Takeshi Yamada et al.
JOURNAL OF IMMUNOLOGY (2019)
Targeted in situ genome-wide profiling with high efficiency for low cell numbers
Peter J. Skene et al.
NATURE PROTOCOLS (2018)
Epigenetic control of CD8+ T cell differentiation
Amanda N. Henning et al.
NATURE REVIEWS IMMUNOLOGY (2018)
The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells
Semir Beyaz et al.
NATURE IMMUNOLOGY (2017)
Histone H3 lysine 4 methyltransferase KMT2D
Eugene Froimchuk et al.
GENE (2017)
Polycomb Repressive Complex 2-Mediated Chromatin Repression Guides Effector CD8+ T Cell Terminal Differentiation and Loss of Multipotency
Simon M. Gray et al.
IMMUNITY (2017)
A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription
Shu-Ping Wang et al.
MOLECULAR CELL (2017)
UTX-guided neural crest function underlies craniofacial features of Kabuki syndrome
Karl B. Shpargel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
An efficient targeted nuclease strategy for high-resolution mapping of DNA binding sites
Peter J. Skene et al.
ELIFE (2017)
The transcription factor Runx3 guards cytotoxic CD8+ effector T cells against deviation towards follicular helper T cell lineage
Qiang Shan et al.
NATURE IMMUNOLOGY (2017)
De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation
Hazem E. Ghoneim et al.
CELL (2017)
Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation
Bingfei Yu et al.
NATURE IMMUNOLOGY (2017)
Detecting broad domains and narrow peaks in ChIP-seq data with hiddenDomains
Joshua Starmer et al.
BMC BIOINFORMATICS (2016)
Epigenetic Dysfunction in Turner Syndrome Immune Cells
Bradly J. Thrasher et al.
CURRENT ALLERGY AND ASTHMA REPORTS (2016)
CD8+ T Cells Utilize Highly Dynamic Enhancer Repertoires and Regulatory Circuitry in Response to Infections
Bing He et al.
IMMUNITY (2016)
Dynamic Changes in Chromatin Accessibility Occur in CD8+ T Cells Responding to Viral Infection
James P. Scott-Browne et al.
IMMUNITY (2016)
Genetic and Epigenetic Regulation of PD-1 Expression
Alexander P. R. Bally et al.
JOURNAL OF IMMUNOLOGY (2016)
Histone Demethylase KDM6A Controls the Mammary Luminal Lineage through Enzyme-Independent Mechanisms
Kyung Hyun Yoo et al.
MOLECULAR AND CELLULAR BIOLOGY (2016)
Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy
Se Jin Im et al.
NATURE (2016)
deepTools2: a next generation web server for deep-sequencing data analysis
Fidel Ramirez et al.
NUCLEIC ACIDS RESEARCH (2016)
The epigenetic landscape of T cell exhaustion
Debattama R. Sen et al.
SCIENCE (2016)
Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade
Kristen E. Pauken et al.
SCIENCE (2016)
T Follicular Helper Cell-Dependent Clearance of a Persistent Virus Infection Requires T Cell Expression of the Histone Demethylase UTX
Kevin D. Cook et al.
IMMUNITY (2015)
Single-cell chromatin accessibility reveals principles of regulatory variation
Jason D. Buenostro et al.
NATURE (2015)
T cell exhaustion during persistent viral infections
Shannon M. Kahan et al.
VIROLOGY (2015)
Histone H3 Lysine 27 demethylases Jmjd3 and Utx are required for T-cell differentiation
Sugata Manna et al.
NATURE COMMUNICATIONS (2015)
EZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansion
Xiang-Ping Yang et al.
SCIENTIFIC REPORTS (2015)
Molecular and cellular insights into T cell exhaustion
E. John Wherry et al.
NATURE REVIEWS IMMUNOLOGY (2015)
Distinct Epigenetic Signatures Delineate Transcriptional Programs during Virus-Specific CD8+ T Cell Differentiation
Brendan E. Russ et al.
IMMUNITY (2014)
Blimp-1 represses CD8 T cell expression of PD-1 using a feed-forward transcriptional circuit during acute viral infection
Peiyuan Lu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
Epigenetic Manipulation Restores Functions of Defective CD8+ T Cells From Chronic Viral Infection
Fuqin Zhang et al.
MOLECULAR THERAPY (2014)
The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells
Makoto Kurachi et al.
NATURE IMMUNOLOGY (2014)
UTX, a Histone H3-Lysine 27 Demethylase, Acts as a Critical Switch to Activate the Cardiac Developmental Program
Seunghee Lee et al.
DEVELOPMENTAL CELL (2012)
Progenitor and Terminal Subsets of CD8+ T Cells Cooperate to Contain Chronic Viral Infection
Michael A. Paley et al.
SCIENCE (2012)
UTX and UTY Demonstrate Histone Demethylase-Independent Function in Mouse Embryonic Development
Karl B. Shpargel et al.
PLOS GENETICS (2012)
Histone Demethylase UTX-1 Regulates C. elegans Life Span by Targeting the Insulin/IGF-1 Signaling Pathway
Chunyu Jin et al.
CELL METABOLISM (2011)
Chronic Virus Infection Enforces Demethylation of the Locus that Encodes PD-1 in Antigen-Specific CD8+ T Cells
Ben Youngblood et al.
IMMUNITY (2011)
BEDTools: a flexible suite of utilities for comparing genomic features
Aaron R. Quinlan et al.
BIOINFORMATICS (2010)
Jmjd3 and UTX Play a Demethylase-Independent Role in Chromatin Remodeling to Regulate T-Box Family Member-Dependent Gene Expression
Sara A. Miller et al.
MOLECULAR CELL (2010)
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
Sven Heinz et al.
MOLECULAR CELL (2010)
Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes
Gillian L. Dalgliesh et al.
NATURE (2010)
Redefining Chronic Viral Infection
Herbert W. Virgin et al.
CELL (2009)
Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
Shawn D. Blackburn et al.
NATURE IMMUNOLOGY (2009)
A Vital Role for Interleukin-21 in the Control of a Chronic Viral Infection
John S. Yi et al.
SCIENCE (2009)
IL-21 Is Required to Control Chronic Viral Infection
Heidi Elsaesser et al.
SCIENCE (2009)
Model-based Analysis of ChIP-Seq (MACS)
Yong Zhang et al.
GENOME BIOLOGY (2008)
UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development
Karl Agger et al.
NATURE (2007)
A histone H3 lysine 27 demethylase regulates animal posterior development
Fei Lan et al.
NATURE (2007)
Molecular signature of CD8+ T cell exhaustion during chronic viral infection
E. John Wherry et al.
IMMUNITY (2007)
Direct interferon-γ signalling and CD8+ T cell memory
Jason K. Whitmire et al.
JOURNAL OF IMMUNOLOGY (2007)
Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis
Sara Wojciechowski et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Restoring function in exhausted CD8 T cells during chronic viral infection
DL Barber et al.
NATURE (2006)
Sensitive and viable identification of antigen-specific CD8+T cells by a flow cytometric assay for degranulation
MR Betts et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2003)
Molecular and functional profiling of memory CD8 T cell differentiation
SM Kaech et al.
CELL (2002)
Functional avidity maturation of CD8+T cells without selection of higher affinity TCR
MK Slifka et al.
NATURE IMMUNOLOGY (2001)