Examining changes in personality following shamanic ceremonial use of ayahuasca

The present study examines the association between the ceremonial use of ayahuasca-a decoction combining the Banistereopsis caapi vine and N,N-Dimethyltryptamine-containing plants-and changes in personality traits as conceived by the Five-Factor model (FFM). We also examine the degree to which demographic characteristics, baseline personality, and acute post-ayahuasca experiences affect personality change. Participants recruited from three ayahuasca healing and spiritual centers in South and Central America (N=256) completed self-report measures of personality at three timepoints (Baseline, Post, 3-month Follow-up). Informant-report measures of the FFM were also obtained (N=110). Linear mixed models were used to examine changes in personality and the moderation of those changes by covariates. The most pronounced change was a reduction in Neuroticism dz(self-reportT1-T2)=-1.00; dz(self-reportT1-T3)=-.85; dz(informant-reportT1-T3)=-.62), reflected in self- and informant-report data. Moderation of personality change by baseline personality, acute experiences, and purgative experiences was also observed.

Automated summary

The study investigates the association between ceremonial use of ayahuasca and changes in personality traits, with the most significant change seen in a reduction in Neuroticism. The moderation of personality change by baseline personality, acute experiences, and purgative experiences was also observed.