4.4 Article

Enhancing Mood, Cognition, and Quality of Life in Pediatric Multiple Sclerosis

Journal

PEDIATRIC DRUGS
Volume 23, Issue 4, Pages 317-329

Publisher

ADIS INT LTD
DOI: 10.1007/s40272-021-00451-5

Keywords

-

Ask authors/readers for more resources

Pediatric-onset multiple sclerosis, accounting for about 5% of all MS cases, primarily diagnosed in adolescence, requires holistic management for pediatric patients to optimize health and well-being. Strategies include disease-modifying therapies, high levels of vitamin D, exercise, and behavioral interventions to improve quality of life.
Pediatric-onset multiple sclerosis (POMS), representing approximately 5% of all MS cases, affects the central nervous system during its ongoing development. POMS is most commonly diagnosed during adolescence but can occur in younger children as well. For pediatric patients with MS, it is critical to manage the full impact of the disease and monitor for any effects on school and social functioning. Disease management includes not only disease-modifying therapies but also strategies to optimize wellbeing. We review the interventions with the highest evidence of ability to improve the disease course and quality of life in POMS. High levels of vitamin D and a diet low in saturated fat are associated with lower relapse rates. Exercise ameliorates fatigue and sleep. Behavioral strategies for sleep hygiene and mood regulation can also improve fatigue and perceived health. POMS management should be addressed holistically, including assessing overall symptom burden as well as the psychological and functional impact of the disease.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.4
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available