Journal
MATERIALS
Volume 14, Issue 9, Pages -Publisher
MDPI
DOI: 10.3390/ma14092096
Keywords
collagen; hydroxyapatite; drugs; bioactive components; metals; nanoparticles; regenerative medicine; tissue engineering
Categories
Funding
- Foundation for Polish Science [POIR.04.04.0000-16D7/18]
- TEAM-NET program of the Foundation for Polish Science - European Union under the European Regional Development Fund (The Multifunctional biologically active composites for applications in bone regenerative medicine) project [POIR.04.04.00-00-16D7/18]
- TEAM-NET program of the Foundation for Polish Science - European Union under the European Regional Development Fund
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Regenerative medicine is rapidly evolving, with scientists worldwide exploring the use of naturally synthesized biomaterials to repair damaged cells. Hydroxyapatite (HAp) and collagen-containing compositions modified with various additives are widely used in biomedical applications such as bone tissue engineering and vascular transplantation.
Regenerative medicine is becoming a rapidly evolving technique in today's biomedical progress scenario. Scientists around the world suggest the use of naturally synthesized biomaterials to repair and heal damaged cells. Hydroxyapatite (HAp) has the potential to replace drugs in biomedical engineering and regenerative drugs. HAp is easily biodegradable, biocompatible, and correlated with macromolecules, which facilitates their incorporation into inorganic materials. This review article provides extensive knowledge on HAp and collagen-containing compositions modified with drugs, bioactive components, metals, and selected nanoparticles. Such compositions consisting of HAp and collagen modified with various additives are used in a variety of biomedical applications such as bone tissue engineering, vascular transplantation, cartilage, and other implantable biomedical devices.
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