Journal
MATERIALS
Volume 14, Issue 10, Pages -Publisher
MDPI
DOI: 10.3390/ma14102647
Keywords
porous tantalum; clinical application; additive manufacturing; surface modification; bone tissue engineering
Categories
Funding
- National Natural Science Foundation of China [81860477, 81860480]
- Jiangxi Provincial Key RD Plan [20181ACG70009]
- Youth Science Fund Project of the Jiangxi Provincial Science and Technology Department [20181BAB215022]
- Young Teachers Research and Development Fund Project of Nanchang University [4209-16100009-PY201818]
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Porous tantalum (Ta) possesses excellent biological and mechanical properties that promote bone growth and implant stability. With the advancement of additive manufacturing, personalized porous Ta-based implants or prostheses have demonstrated significant clinical value in treatment.
Porous tantalum (Ta) is a promising biomaterial and has been applied in orthopedics and dentistry for nearly two decades. The high porosity and interconnected pore structure of porous Ta promise fine bone ingrowth and new bone formation within the inner space, which further guarantee rapid osteointegration and bone-implant stability in the long term. Porous Ta has high wettability and surface energy that can facilitate adherence, proliferation and mineralization of osteoblasts. Meanwhile, the low elastic modulus and high friction coefficient of porous Ta allow it to effectively avoid the stress shield effect, minimize marginal bone loss and ensure primary stability. Accordingly, the satisfactory clinical application of porous Ta-based implants or prostheses is mainly derived from its excellent biological and mechanical properties. With the advent of additive manufacturing, personalized porous Ta-based implants or prostheses have shown their clinical value in the treatment of individual patients who need specially designed implants or prosthesis. In addition, many modification methods have been introduced to enhance the bioactivity and antibacterial property of porous Ta with promising in vitro and in vivo research results. In any case, choosing suitable patients is of great importance to guarantee surgical success after porous Ta insertion.
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