Journal
INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
Volume 22, Issue 1, Pages 185-189Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/1534734621999269
Keywords
necrobiosis lipoidica; diabetes mellitus; glucose control; doxycycline
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Necrobiosis lipoidica is a granulomatous skin condition commonly associated with diabetes, with a low incidence rate. The cause of the disease is still unclear, and although topical steroids are widely accepted for treatment, the effect of glucose control is still debated.
Necrobiosis lipoidica is a granulomatous skin condition commonly associated with diabetes. When associated with diabetes mellitus, the name expands to necrobiosis lipoidica diabeticorum (NLD). In these patients, this rare condition has an incidence rate of 0.3% to 1.6%. The cause of NLD remains unknown even though many speculations exist in the medical literature. The treatment of this condition has most researchers agreeing on the use of topical steroids for the anti-inflammatory effect on NLD; however, the role of glucose control in the treatment of this disorder has been debatable. The following case presents a patient who, despite better glucose control, did not improve until the introduction of doxycycline.
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