4.5 Article

Primitive neuroectodermal tumor of the cervix diagnosed during pregnancy: a rare case report with discussion

Journal

BMC PREGNANCY AND CHILDBIRTH
Volume 21, Issue 1, Pages -

Publisher

BMC
DOI: 10.1186/s12884-021-03859-6

Keywords

Pregnancy; Cervix; Primitive neuroectodermal tumor; Treatment

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PNET during pregnancy is a rare and complex condition that requires an individualized treatment plan based on gestational age. Timely surgical treatment can significantly prolong patient survival, but may also result in fetal loss and the inability to continue pregnancy.
Background Primitive neuroectodermal tumor (PNET) is a relatively rare malignant small round cell tumor, and the occurrence of cervical PNET during pregnancy is extremely rare. Case presentation A case of pregnancy complicated by PNET at our hospital was reported. A 19-year-old pregnant woman presented to the hospital due to multiple instances of vaginal bleeding during the first and second trimesters. She was initially considered for threatened abortion but was ultimately diagnosed with cervical PNET. No standard treatment plan has been developed for pregnant women with this tumor. After completing the necessary examinations, doctors cooperated with the patient and her family to develop a surgical treatment plan. The patient recovered well after surgery, but she refused radiotherapy and chemotherapy. After nearly 3 years of follow-up visits, the patient is alive with no signs of recurrence. Conclusions PNET during pregnancy is a rare but complex condition. It is necessary to devise an individualized treatment plan according to gestational age. Timely surgical treatment can significantly prolong the survival time of patients but may also lead to fetal loss and the inability to carry a pregnancy.

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