Related references
Note: Only part of the references are listed.Predictive biomarkers and mechanisms underlying resistance to PD1/PD-L1 blockade cancer immunotherapy
Daixi Ren et al.
MOLECULAR CANCER (2020)
Interleukin-2 signals converge in a lymphoid-dendritic cell pathway that promotes anticancer immunity
Miro E. Raeber et al.
SCIENCE TRANSLATIONAL MEDICINE (2020)
PD-L1 on dendritic cells attenuates T cell activation and regulates response to immune checkpoint blockade
Qi Peng et al.
NATURE COMMUNICATIONS (2020)
An IL-2-grafted antibody immunotherapy with potent efficacy against metastatic cancer
Dilara Sahin et al.
NATURE COMMUNICATIONS (2020)
A First-in-Human Study and Biomarker Analysis of NKTR-214, a Novel 1L2Rβγ-Biased Cytokine, in Patients with Advanced or Metastatic Solid Tumors
Salah-Eddine Bentebibel et al.
CANCER DISCOVERY (2019)
A pan-cancer perspective of matrix metalloproteases (MMP) gene expression profile and their diagnostic/prognostic potential
Emily Gobin et al.
BMC CANCER (2019)
A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8+ T-cell response and effective tumor control
Zhichen Sun et al.
NATURE COMMUNICATIONS (2019)
PD-L1 and Emerging Biomarkers in Immune Checkpoint Blockade Therapy
Tricia R. Cottrell et al.
CANCER JOURNAL (2018)
PD-L1 on host cells is essential for PD-L1 blockade-mediated tumor regression
Haidong Tang et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Host expression of PD-L1 determines efficacy of PD-L1 pathway blockade-mediated tumor regression
Heng Lin et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Nanoparticle anchoring targets immune agonists to tumors enabling anti-cancer immunity without systemic toxicity
Yuan Zhang et al.
NATURE COMMUNICATIONS (2018)
IL-2/CD25: A Long-Acting Fusion Protein That Promotes Immune Tolerance by Selectively Targeting the IL-2 Receptor on Regulatory T Cells
Natasha C. Ward et al.
JOURNAL OF IMMUNOLOGY (2018)
Effector-attenuating Substitutions That Maintain Antibody Stability and Reduce Toxicity in Mice
Megan Lo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity
Vikram R. Juneja et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
Interferon-γ derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity
Purnima Bhat et al.
CELL DEATH & DISEASE (2017)
Potent antitumour activity of interleukin-2-Fc fusion proteins requires Fc-mediated depletion of regulatory T-cells
Rodrigo Vazquez-Lombardi et al.
NATURE COMMUNICATIONS (2017)
Regulatory T cells control toxicity in a humanized model of IL-2 therapy
Yan Li et al.
NATURE COMMUNICATIONS (2017)
Structural basis of a novel heterodimeric Fc for bispecific antibody production
Hudie Wei et al.
ONCOTARGET (2017)
Cathepsin L and B as Potential Markers for Liver Fibrosis: Insights From Patients and Experimental Models
Mansi Manchanda et al.
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY (2017)
Cergutuzumab amunaleukin (CEA-IL2v), a CEA- targeted IL-2 variant- based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional IL-2-based immunocytokines
Christian Klein et al.
ONCOIMMUNOLOGY (2017)
Surgery for Cancer: A Trigger for Metastases
Samer Tohme et al.
CANCER RESEARCH (2017)
NKTR-214, an Engineered Cytokine with Biased IL2 Receptor Binding, Increased Tumor Exposure, and Marked Efficacy in Mouse Tumor Models
Deborah H. Charych et al.
CLINICAL CANCER RESEARCH (2016)
Improved cancer immunotherapy by a CD25-mimobody conferring selectivity to human interleukin-2
Natalia Arenas-Ramirez et al.
Science Translational Medicine (2016)
Improved Efficacy of Neoadjuvant Compared to Adjuvant Immunotherapy to Eradicate Metastatic Disease
Jing Liu et al.
CANCER DISCOVERY (2016)
Site-Specific PEGylation of Therapeutic Proteins
Jonathan K. Dozier et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Immunoexpression of Metalloproteinases 2 and 14 and TIMP-2 Inhibitor in Main Types of Primary Gastric Carcinomas and Lymph Node Metastasis
Daniel Cordeiro Gurgel et al.
PATHOLOGY & ONCOLOGY RESEARCH (2015)
Interleukin-2 at the Crossroads of Effector Responses, Tolerance, and Immunotherapy
Wei Liao et al.
IMMUNITY (2013)
Endocytosis and Cancer
Ira Mellman et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'
Aron M. Levin et al.
NATURE (2012)
Mechanisms of T-reg suppression: still a long way to go
Dario A. A. Vignali
FRONTIERS IN IMMUNOLOGY (2012)
Development of an attenuated interleukin-2 fusion protein that can be activated by tumour-expressed proteases
John Puskas et al.
IMMUNOLOGY (2011)
Matrix metalloproteinase-2 (MMP-2) and MMP-9 expression in invasive ductal carcinoma of the breast
Yurdanur Sullu et al.
PATHOLOGY RESEARCH AND PRACTICE (2011)
IFN-γ and TNF-α secretion by CD4+ and CD8+ TCRαβ+ T-cell clones derived early after allogeneic bone marrow transplantation
Øystein Bruserud et al.
EUROPEAN JOURNAL OF HAEMATOLOGY (2010)
Comparative study of the expression of metalloproteases and their inhibitors in different localizations within primary tumours and in metastatic lymph nodes of breast cancer
Maria Fernanda Garcia et al.
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (2010)
IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor α subunit CD25
Sven Letourneau et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Improved IL-2 immunotherapy by selective stimulation of IL-2 receptors on lymphocytes and endothelial cells
Carsten Krieg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Auditing protein therapeutics management by professional APCs:: Toward prevention of immune responses against therapeutic proteins
Suryasarathi Dasgupta et al.
JOURNAL OF IMMUNOLOGY (2008)
Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis
Veronica C. Ardi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Urokinase-type plasminogen activator supports liver repair independent of its cellular receptor
Kumar Shanmukhappa et al.
BMC GASTROENTEROLOGY (2006)
Matrix metalloproteinases and tumor metastasis
EI Deryugina et al.
CANCER AND METASTASIS REVIEWS (2006)
Structure of the quaternary complex of interleukin-2 with its α, β, and γc receptors
XQ Wang et al.
SCIENCE (2005)
Rapid production of TNF-α following TCR engagement of naive CD8 T cells
MA Brehm et al.
JOURNAL OF IMMUNOLOGY (2005)
Biological, histological, and clinical impact of preoperative IL-2 administration in radically operable gastric cancer patients
F Romano et al.
JOURNAL OF SURGICAL ONCOLOGY (2004)
Comparative analysis of lymphocyte activation marker expression and cytokine secretion profile in stimulated human peripheral blood mononuclear cell cultures: an in vitro model to monitor cellular immune function
M Reddy et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2004)
Share Paper
