Related references
Note: Only part of the references are listed.Subcellular Localization And Formation Of Huntingtin Aggregates Correlates With Symptom Onset And Progression In A Huntington'S Disease Model
Christian Landles et al.
BRAIN COMMUNICATIONS (2020)
The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis
Daniel Gestaut et al.
CELL (2019)
Stem cell-derived cranial and spinal motor neurons reveal proteostatic differences between ALS resistant and sensitive motor neurons
Disi Ann et al.
ELIFE (2019)
Natural Products as Modulators of the Proteostasis Machinery: Implications in Neurodegenerative Diseases
Karina Cuanalo-Contreras et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Polyubiquitin chain-induced p62 phase separation drives autophagic cargo segregation
Daxiao Sun et al.
CELL RESEARCH (2018)
Activation of p62/SQSTM1-Keap1-Nuclear Factor erythroid 2-Related Factor 2 Pathway in Cancer
Yoshinobu Ichimura et al.
FRONTIERS IN ONCOLOGY (2018)
Protein misfolding, aggregation, and conformational strains in neurodegenerative diseases
Claudio Soto et al.
NATURE NEUROSCIENCE (2018)
Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter
Do Hoon Kwon et al.
NATURE COMMUNICATIONS (2018)
Regulation of selective autophagy: the p62/SQSTM1 paradigm
Trond Lamark et al.
SIGNALLING MECHANISMS IN AUTOPHAGY (2017)
When Proteostasis Goes Bad: Protein Aggregation in the Cell
Mona Radwan et al.
IUBMB LIFE (2017)
UXT Is a LOX-PP Interacting Protein That Modulates Estrogen Receptor Alpha Activity in Breast Cancer Cells
Nuria Sanchez-Morgan et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2017)
Receptor oligomerization guides pathway choice between proteasomal and autophagic degradation
Kefeng Liu et al.
NATURE CELL BIOLOGY (2017)
The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy
Yong Tae Kwon et al.
TRENDS IN BIOCHEMICAL SCIENCES (2017)
Misfolded polypeptides are selectively recognized and transported toward aggresomes by a CED complex
Joori Park et al.
NATURE COMMUNICATIONS (2017)
p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis
Hyunjoo Cha-Molstad et al.
NATURE COMMUNICATIONS (2017)
Keap1/Cullin3 Modulates p62/SQSTM1 Activity via UBA Domain Ubiquitination
YouJin Lee et al.
CELL REPORTS (2017)
Caspases and their substrates
Olivier Julien et al.
CELL DEATH AND DIFFERENTIATION (2017)
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Daniel J. Klionsky et al.
AUTOPHAGY (2016)
LC3/GABARAP family proteins: autophagy-(un) related functions
Marco B. E. Schaaf et al.
FASEB JOURNAL (2016)
Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice
Shinji Hadano et al.
HUMAN MOLECULAR GENETICS (2016)
Mechanisms of Selective Autophagy
Gabriele Zaffagnini et al.
JOURNAL OF MOLECULAR BIOLOGY (2016)
Ubiquitin-Dependent And Independent Signals In Selective Autophagy
Aliaksandr Khaminets et al.
TRENDS IN CELL BIOLOGY (2016)
Neuronal Aggregates: Formation, Clearance, and Spreading
Junghyun Lim et al.
DEVELOPMENTAL CELL (2015)
Assays to monitor aggrephagy
Alf Hakon Lystad et al.
METHODS (2015)
Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding
Hyunjoo Cha-Molstad et al.
NATURE CELL BIOLOGY (2015)
The Selective Autophagy Receptor p62 Forms a Flexible Filamentous Helical Scaffold
Rodolfo Ciuffa et al.
CELL REPORTS (2015)
Oligomerization of p62 allows for selection of ubiquitinated cargo and isolation membrane during selective autophagy
Bettina Wurzer et al.
ELIFE (2015)
Sqstm1 knock-down causes a locomotor phenotype ameliorated by rapamycin in a zebrafish model of ALS/FTLD
Serena Lattante et al.
HUMAN MOLECULAR GENETICS (2015)
Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies
Aaron Ciechanover et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2015)
Prefoldin prevents aggregation of α-synuclein
Mariko Takano et al.
BRAIN RESEARCH (2014)
Chaperone-mediated autophagy: roles in disease and aging
Ana Maria Cuervo et al.
CELL RESEARCH (2014)
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
Ophir Shalem et al.
SCIENCE (2014)
Human Prefoldin Inhibits Amyloid-β (Aβ) Fibrillation and Contributes to Formation of Nontoxic A/β Aggregates
Karin Margareta Soergjerd et al.
BIOCHEMISTRY (2013)
The role of ALFY in selective autophagy
P. Isakson et al.
CELL DEATH AND DIFFERENTIATION (2013)
Prefoldin Protects Neuronal Cells from Polyglutamine Toxicity by Preventing Aggregation Formation
Erika Tashiro et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Neuromuscular effects of G93A-SOD1 expression in zebrafish
Stacey A. Sakowski et al.
MOLECULAR NEURODEGENERATION (2012)
SQSTM1 mutations in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Elisa Rubino et al.
NEUROLOGY (2012)
Alfa-class prefoldin protein UXT is a novel interacting partner of Amyotrophic Lateral Sclerosis 2 (Als2) protein
Izzet Enunlu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins
Martin Gamerdinger et al.
EMBO REPORTS (2011)
p62 targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding
Eisuke Itakura et al.
JOURNAL OF CELL BIOLOGY (2011)
The elimination of accumulated and aggregated proteins: A role for aggrephagy in neurodegeneration
Ai Yamamoto et al.
NEUROBIOLOGY OF DISEASE (2011)
Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth
Philipp Wild et al.
SCIENCE (2011)
p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy
Terje Hoyvarde Clausen et al.
AUTOPHAGY (2010)
The Selective Macroautophagic Degradation of Aggregated Proteins Requires the PI3P-Binding Protein Alfy
Maria Filimonenko et al.
MOLECULAR CELL (2010)
Quality Control Against Misfolded Proteins in the Cytosol: A Network for Cell Survival
Hiroshi Kubota
JOURNAL OF BIOCHEMISTRY (2009)
Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism
Jozsef Gal et al.
JOURNAL OF NEUROCHEMISTRY (2009)
A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates
Vladimir Kirkin et al.
MOLECULAR CELL (2009)
Autophagy and the ubiquitin-proteasome system: Collaborators in neuroprotection
Natalia B. Nedelsky et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2008)
Overexpression of mutant superoxide dismutase 1 causes a motor axonopathy in the zebrafish
Robin Lemmens et al.
HUMAN MOLECULAR GENETICS (2007)
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
Serhiy Pankiv et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
UXT is a novel and essential cofactor in the NF-κB transcriptional enhanceosome
Shaogang Sui et al.
JOURNAL OF CELL BIOLOGY (2007)
Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations:: Potential factors in amyloid plaque formation
Holly Oakley et al.
JOURNAL OF NEUROSCIENCE (2006)
Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria
HX Deng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
HDAC6 and microtubules are required for autophagic degradation of aggregated Huntingtin
A Iwata et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
UXT is a novel centrosomal protein essential for cell viability
HW Zhao et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
G Bjorkoy et al.
JOURNAL OF CELL BIOLOGY (2005)
The LIM protein Ajuba influences interleukin-1-induced NF-κB activation by affecting the assembly and activity of the protein kinase Cζ/p62/TRAF6 signaling complex
YF Feng et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Structure of the ubiquitin-associated domain of p62 (SQSTM1) and implications for mutations that cause Paget's disease of bone
B Ciani et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Protein quality control:: U-box-containing E3 ubiquitin ligases join the fold
DM Cyr et al.
TRENDS IN BIOCHEMICAL SCIENCES (2002)
Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading
JR Subramaniam et al.
NATURE NEUROSCIENCE (2002)
The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation
K Suzuki et al.
EMBO JOURNAL (2001)
The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation
GC Meacham et al.
NATURE CELL BIOLOGY (2001)
Structure of the molecular chaperone prefoldin: Unique interaction of multiple coiled coil tentacles with unfolded proteins
R Siegert et al.
CELL (2000)
Share Paper
