A rapid, accurate, scalable, and portable testing system for COVID-19 diagnosis

Article Medical Laboratory Technology

Rapid and Extraction-Free Detection of SARS-CoV-2 from Saliva by Colorimetric Reverse-Transcription Loop-Mediated Isothermal Amplification

Matthew A. Lalli et al.

Summary: The study developed a rapid colorimetric assay for SARS-CoV-2 detection using saliva samples without RNA extraction, achieving high accuracy and sensitivity.

CLINICAL CHEMISTRY (2021)

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Article Immunology

Self-Collected Oral Fluid and Nasal Swabs Demonstrate Comparable Sensitivity to Clinician Collected Nasopharyngeal Swabs for Coronavirus Disease 2019 Detection

N. Kojima et al.

Summary: Both supervised oral fluid and nasal swab specimens performed similarly to clinician-collected nasopharyngeal swab specimens in detecting SARS-CoV-2, and none of the positive participants were detected using any sample type.

CLINICAL INFECTIOUS DISEASES (2021)

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Article Multidisciplinary Sciences

Test sensitivity is secondary to frequency and turnaround time for COVID-19 screening

Daniel B. Larremore et al.

Summary: The COVID-19 pandemic has led to a public health crisis due to the spread of SARS-CoV-2 through presymptomatic, symptomatic, and asymptomatic individuals. Effective population screening for the virus is essential for reopening societies and controlling its spread, with testing frequency and reporting speed playing crucial roles in its success. Test sensitivity is only marginally important compared to these factors.

SCIENCE ADVANCES (2021)

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Review Pharmacology & Pharmacy