4.6 Review

Neo-LVOT and Transcatheter Mitral Valve Replacement Expert Recommendations

Journal

JACC-CARDIOVASCULAR IMAGING
Volume 14, Issue 4, Pages 843-866

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.jcmg.2020.09.027

Keywords

LVOT; LVOT obstruction; neo-LVOT; transcatheter mitral valve replacement

Funding

  1. Boston Scientific
  2. 3Mensio
  3. Circle CVI
  4. Medis
  5. Siemens Healthineers
  6. Edwards Lifesciences
  7. Medtronic
  8. Abbott

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This paper discusses the concept of neo-left ventricular outflow tract (LVOT) in transcatheter mitral valve replacement (TMVR) and provides a step-by-step computed tomography methodology to segment and measure the neo-LVOT. It also examines the technical and hemodynamic factors in assessing the neo-LVOT, along with expert recommendations on reducing the risk of LVOT obstruction and post-procedural complications.
With the advent of transcatheter mitral valve replacement (TMVR), the concept of the neo-left ventricular outflow tract (LVOT) was introduced and remains an essential component of treatment planning. This paper describes the LVOT anatomy and provides a step-by-step computed tomography methodology to segment and measure the neo-LVOT while discussing the current evidence and outstanding challenges. It also discusses the technical and hemodynamic factors that play a major role in assessing the neo-LVOT. A summary of expert-based recommendations about the overall risk of LVOT obstruction in different scenarios is presented along with the currently available methods to reduce the risk of LVOT obstruction and other post-procedural complications. (C) 2021 by the American College of Cardiology Foundation.

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