Related references
Note: Only part of the references are listed.Novel anti-Wolbachia drugs, a new approach in the treatment and prevention of veterinary filariasis?
Joseph D. Turner et al.
VETERINARY PARASITOLOGY (2020)
Antivenom Neutralization of Coagulopathic Snake Venom Toxins Assessed by Bioactivity Profiling Using Nanofractionation Analytics
Chunfang Xie et al.
TOXINS (2020)
Varespladib (LY315920) and Methyl Varespladib (LY333013) Abrogate or Delay Lethality Induced by Presynaptically Acting Neurotoxic Snake Venoms
Jose Maria Gutierrez et al.
TOXINS (2020)
Preclinical validation of a repurposed metal chelator as an early-intervention therapeutic for hemotoxic snakebite
Laura-Oana Albulescu et al.
SCIENCE TRANSLATIONAL MEDICINE (2020)
Guinea worm in domestic dogs in Chad: A description and analysis of surveillance data
Sarah Anne J. Guagliardo et al.
PLOS NEGLECTED TROPICAL DISEASES (2020)
Repurposing Cancer Drugs Batimastat and Marimastat to Inhibit the Activity of a Group I Metalloprotease from the Venom of the Western Diamondback Rattlesnake,Crotalus atrox
Harry J. Layfield et al.
TOXINS (2020)
SnakeMap: four years of experience with a national small animal snake envenomation registry
M. Boller et al.
AUSTRALIAN VETERINARY JOURNAL (2020)
Causes and Consequences of Snake Venom Variation
Nicholas R. Casewell et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2020)
Development of high-throughput screening assays for profiling snake venom phospholipase A2 activity after chromatographic fractionation
Kristina B. M. Still et al.
TOXICON (2020)
Challenges and prospects of snake antivenom supply in sub-Saharan Africa
Abdulrazaq G. Habib et al.
PLOS NEGLECTED TROPICAL DISEASES (2020)
An analysis of preclinical efficacy testing of antivenoms for sub-Saharan Africa: Inadequate independent scrutiny and poor-quality reporting are barriers to improving snakebite treatment and management
Stuart Ainsworth et al.
PLOS NEGLECTED TROPICAL DISEASES (2020)
Interventions for the management of snakebite envenoming: An overview of systematic reviews
Soumyadeep Bhaumik et al.
PLOS NEGLECTED TROPICAL DISEASES (2020)
Novel Snakebite Therapeutics Must Be Tested in Appropriate Rescue Models to Robustly Assess Their Preclinical Efficacy
Cecilie Knudsen et al.
TOXINS (2020)
Neutralizing Effects of Small Molecule Inhibitors and Metal Chelators on Coagulopathic Viperinae Snake Venom Toxins
Chunfang Xie et al.
BIOMEDICINES (2020)
A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite
Laura-Oana Albulescu et al.
NATURE COMMUNICATIONS (2020)
Peptide Inhibitors of the α-Cobratoxin-Nicotinic Acetylcholine Receptor Interaction
Timothy Lynagh et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Neglected tropical diseases: elimination and eradication
Christopher Bodimeade et al.
CLINICAL MEDICINE (2019)
Ultra-large library docking for discovering new chemotypes
Jiankun Lyu et al.
NATURE (2019)
Preclinical development of an oral anti-Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis
Mark J. Taylor et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
Strategy for a globally coordinated response to a priority neglected tropical disease: Snakebite envenoming
David J. Williams et al.
PLOS NEGLECTED TROPICAL DISEASES (2019)
Discovery of ABBV-4083, a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity
Thomas W. von Geldern et al.
PLOS NEGLECTED TROPICAL DISEASES (2019)
Topical and Transdermal Drug Delivery: From Simple Potions to Smart Technologies
Heather A. E. Benson et al.
CURRENT DRUG DELIVERY (2019)
How can monoclonal antibodies be harnessed against neglected tropical diseases and other infectious diseases?
Andreas H. Laustsen
EXPERT OPINION ON DRUG DISCOVERY (2019)
Snakebite-emerging from the shadows of neglect
[Anonymous]
LANCET (2019)
Reviewing evidence of the clinical effectiveness of commercially available antivenoms in sub-Saharan Africa identifies the need for a multi-centre, multi-antivenom clinical trial
Julien Potet et al.
PLOS NEGLECTED TROPICAL DISEASES (2019)
The Urgent Need to Develop Novel Strategies for the Diagnosis and Treatment of Snakebites
Harry F. Williams et al.
TOXINS (2019)
A Decoy-Receptor Approach Using Nicotinic Acetylcholine Receptor Mimics Reveals Their Potential as Novel Therapeutics Against Neurotoxic Snakebite
Laura-Oana Albulescu et al.
FRONTIERS IN PHARMACOLOGY (2019)
Multifunctional Toxins in Snake Venoms and Therapeutic Implications: From Pain to Hemorrhage and Necrosis
Camila R. Ferraz et al.
FRONTIERS IN ECOLOGY AND EVOLUTION (2019)
Structural basis for phospholipase A2-like toxin inhibition by the synthetic compound Varespladib (LY315920)
Guilherme H. M. Salvador et al.
SCIENTIFIC REPORTS (2019)
Investigation of protein-protein interactions and hot spot region between PD-1 and PD-L1 by fragment molecular orbital method
Hocheol Lim et al.
SCIENTIFIC REPORTS (2019)
A Taxon-Specific and High-Throughput Method for Measuring Ligand Binding to Nicotinic Acetylcholine Receptors
Christina N. Zdenek et al.
TOXINS (2019)
AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis
W. David Hong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Neutralizing properties of LY315920 toward snake venom group I and II myotoxic phospholipases A(2)
Wendy Bryan-Quiros et al.
TOXICON (2019)
The time is now: a call for action to translate recent momentum on tackling tropical snakebite into sustained benefit for victims
Robert A. Harrison et al.
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE (2019)
Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides
Rachel H. Clare et al.
NATURE COMMUNICATIONS (2019)
Inventing new therapies without reinventing the wheel: the power of drug repurposing
Andreas Papapetropoulos et al.
BRITISH JOURNAL OF PHARMACOLOGY (2018)
Vulnerability to snakebite envenoming: a global mapping of hotspots
Joshua Longbottom et al.
LANCET (2018)
Matrix Metalloproteinase Inhibitors in Cancer Therapy: Turning Past Failures Into Future Successes
Arthur Winer et al.
MOLECULAR CANCER THERAPEUTICS (2018)
Exploration of the Inhibitory Potential of Varespladib for Snakebite Envenomation
Yiding Wang et al.
MOLECULES (2018)
Venom proteomics and antivenom neutralization for the Chinese eastern Russell's viper, Daboia siamensis from Guangxi and Taiwan
Kae Yi Tan et al.
SCIENTIFIC REPORTS (2018)
Alternative treatment strategies to accelerate the elimination of onchocerciasis
Michel Boussinesq et al.
INTERNATIONAL HEALTH (2018)
For as Long as Necessary: Examining 30 years of MSD's† Focus on Achieving Elimination of Onchocerciasis and Lymphatic Filariasis
Kenneth M. Gustavsen et al.
INTERNATIONAL HEALTH (2018)
Why snakebite patients in Myanmar seek traditional healers despite availability of biomedical care at hospitals? Community perspectives on reasons
Eliza Schioldann et al.
PLOS NEGLECTED TROPICAL DISEASES (2018)
Challenges and recent progress in drug discovery for tropical diseases
Manu De Rycker et al.
NATURE (2018)
Delayed Oral LY333013 Rescues Mice from Highly Neurotoxic, Lethal Doses of Papuan Taipan (Oxyuranus scutellatus) Venom
Matthew R. Lewin et al.
TOXINS (2018)
Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017
Spencer L. G. James et al.
LANCET (2018)
The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis
Jeff Janes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Delayed LY333013 (Oral) and LY315920 (Intravenous) Reverse Severe Neurotoxicity and Rescue Juvenile Pigs from Lethal Doses of Micrurus fulvius (Eastern Coral Snake) Venom
Matthew R. Lewin et al.
TOXINS (2018)
Coagulotoxic Cobras: Clinical Implications of Strong Anticoagulant Actions of African Spitting Naja Venoms That Are Not Neutralised by Antivenom but Are by LY315920 (Varespladib)
Matyas A. Bittenbinder et al.
TOXINS (2018)
Developing Small Molecule Therapeutics for the Initial and Adjunctive Treatment of Snakebite
Tommaso C. Bulfone et al.
JOURNAL OF TROPICAL MEDICINE (2018)
Peptidomimetic hydroxamate metalloproteinase inhibitors abrogate local and systemic toxicity induced by Echis ocellatus (saw-scaled) snake venom
Ana Silvia Arias et al.
TOXICON (2017)
Preclinical antivenom-efficacy testing reveals potentially disturbing deficiencies of snakebite treatment capability in East Africa
Robert A. Harrison et al.
PLOS NEGLECTED TROPICAL DISEASES (2017)
Recombinant snakebite antivenoms: A cost-competitive solution to a neglected tropical disease?
Andreas H. Laustsen et al.
PLOS NEGLECTED TROPICAL DISEASES (2017)
Multipurpose HTS Coagulation Analysis: Assay Development and Assessment of Coagulopathic Snake Venoms
Kristina B. M. Still et al.
TOXINS (2017)
Coralsnake Venomics: Analyses of Venom Gland Transcriptomes and Proteomes of Six Brazilian Taxa
Steven D. Aird et al.
TOXINS (2017)
A Review and Database of Snake Venom Proteomes
Theo Tasoulis et al.
TOXINS (2017)
Snakebite envenoming
Jose Maria Gutierrez et al.
NATURE REVIEWS DISEASE PRIMERS (2017)
Identification and prioritization of novel anti-Wolbachia chemotypes from screening a 10,000-compound diversity library
Kelly L. Johnston et al.
SCIENCE ADVANCES (2017)
Haemotoxic snake venoms: their functional activity, impact on snakebite victims and pharmaceutical promise
Julien Slagboom et al.
BRITISH JOURNAL OF HAEMATOLOGY (2017)
Adverse reactions to snake antivenom, and their prevention and treatment
H. Asita de Silva et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2016)
The Role of Nurses and Community Health Workers in Confronting Neglected Tropical Diseases in Sub-Saharan Africa: A Systematic Review
Andrew G. Corley et al.
PLOS NEGLECTED TROPICAL DISEASES (2016)
Hemorrhage Caused by Snake Venom Metalloproteinases: A Journey of Discovery and Understanding
Jose Maria Gutierrez et al.
TOXINS (2016)
Varespladib (LY315920) Appears to Be a Potent, Broad-Spectrum, Inhibitor of Snake Venom Phospholipase A2 and a Possible Pre-Referral Treatment for Envenomation
Matthew Lewin et al.
TOXINS (2016)
Africa braced for snakebite crisis
Quirin Schiermeier
NATURE (2015)
Antivenoms for Snakebite Envenoming: What Is in the Research Pipeline?
Emilie Alirol et al.
PLOS NEGLECTED TROPICAL DISEASES (2015)
Varespladib and Cardiovascular Events in Patients With an Acute Coronary Syndrome The VISTA-16 Randomized Clinical Trial
Stephen J. Nicholls et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2014)
Anti-Wolbachia drug discovery and development: safe macrofilaricides for onchocerciasis and lymphatic filariasis
Mark J. Taylor et al.
PARASITOLOGY (2014)
The role of modern drug discovery in the fight against neglected and tropical diseases
Jeremy N. Burrows et al.
MEDCHEMCOMM (2014)
Neurotoxicity in Snakebite-The Limits of Our Knowledge
Udaya K. Ranawaka et al.
PLOS NEGLECTED TROPICAL DISEASES (2013)
Reversal of experimental paralysis in a human by intranasal neostigmine aerosol suggests a novel approach to the early treatment of neurotoxic envenomation
Matthew R. Lewin et al.
CLINICAL CASE REPORTS (2013)
Consequences of Neglect: Analysis of the Sub-Saharan African Snake Antivenom Market and the Global Context
Nicholas I. Brown
PLOS NEGLECTED TROPICAL DISEASES (2012)
The Global Snake Bite Initiative: an antidote for snake bite
David Williams et al.
LANCET (2010)
Rescuing the bottom billion through control of neglected tropical diseases
Peter J. Hotez et al.
LANCET (2009)
Snake Envenoming: A Disease of Poverty
Robert A. Harrison et al.
PLOS NEGLECTED TROPICAL DISEASES (2009)
Failure of a new antivenom to treat Echis ocellatus snake bite in rural Ghana:: the importance of quality surveillance
L. E. Visser et al.
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE (2008)
Unscrupulous marketing of snake bite antivenoms in Africa and Papua New Guinea: choosing the right product - 'What's in a name?'
David A. Warrell
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE (2008)
The Global Burden of Snakebite: A Literature Analysis and Modelling Based on Regional Estimates of Envenoming and Deaths
Anuradhani Kasturiratne et al.
PLOS MEDICINE (2008)
The evolution of the vertebrate metzincins;: insights from Ciona intestinalis and Danio rerio
Julie Huxley-Jones et al.
BMC EVOLUTIONARY BIOLOGY (2007)
Neutralization of the haemorrhagic activities of viperine snake venoms and venom metalloproteinases using synthetic peptide inhibitors and chelators
J.-M. Howes et al.
TOXICON (2007)
Snake antivenoms
DG Lalloo et al.
JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY (2003)
Crisis in snake antivenom supply for Africa
RDG Theakston et al.
LANCET (2000)
Inhibition of local hemorrhage and dermonecrosis induced by Bothrops asper snake venom:: Effectiveness of early in situ administration of the peptidomimetic metalloproteinase inhibitor batimastat and the chelating agent CaNa2EDTA
A Rucavado et al.
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2000)