Journal
TRENDS IN CELL BIOLOGY
Volume 31, Issue 7, Pages 520-524Publisher
CELL PRESS
DOI: 10.1016/j.tcb.2021.03.011
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Funding
- National Natural Science Foundation of China [82072701, 11972280]
- China Postdoctoral Science Foundation [2019T120920]
- Clinical Research Award of the First Affiliated Hospital of Xi'an Jiaotong University, China [XJTU1AFCRF2019001]
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Physical cues in the tumor microenvironment have been recognized as new hallmarks of cancer, with the potential to serve as new targets for improved cancer immunotherapy, due to their synergistic contribution to low response rates.
A low response rate is the major challenge for existing cancer immunotherapies. Physical cues in the tumor microenvironment (TME) have been recognized as new hallmarks of cancer, which may synergistically contribute to low immunotherapy response. Recent evidence indicates that the physical hallmarks of cancer hold great potential as new targets for improved immunotherapy.
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