Journal
TRENDS IN BIOCHEMICAL SCIENCES
Volume 46, Issue 7, Pages 519-521Publisher
CELL PRESS
DOI: 10.1016/j.tibs.2021.03.005
Keywords
-
Categories
Ask authors/readers for more resources
The flavivirus nonstructural protein 1 (NS1) plays an important role in disease progression, and two new studies reveal the mechanism of neutralization by anti-NS1 antibodies, which have been shown to confer protection against severe dengue disease.
The flavivirus genus consists of several major human pathogens including dengue (DENV) and Zika viruses. The flavivirus nonstructural protein 1 (NS1) plays an important role in disease progression, for example, in the development of severe dengue disease. Anti-NS1 antibodies have been shown to confer protection, and two new studies by Biering et al. and Modhiran et al. on the structure of NS1:antibody complexes reveal their mechanism of neutralization.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available