4.4 Article

Application of allylic amine formation from aziridine-2-ol under Appel reaction condition: Synthesis of N-(tert-butoxycarbonyl)-D-vinyl glycine methyl ester

Journal

TETRAHEDRON LETTERS
Volume 73, Issue -, Pages -

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2021.153119

Keywords

Aziridine-2-alcohol; Allyl amine; Ring opening; Birch reaction; Aziridinium ion

Funding

  1. CSIR, New Delhi [21(1111)/20/EMR-II]

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The formation of allyl amine from aziridine-2-alcohol was achieved through PPh3/I-2/imidazolde mediation for the synthesis of N-(tert-butoxycarbonyl)-D-vinyl glycine methyl ester.
PPh3/I-2/imidazolde mediated allyl amine formation from aziridine-2-alcohol was explored for the synthesis of N-(tert-butoxycarbonyl)-D-vinyl glycine methyl ester. (C) 2021 Published by Elsevier Ltd.

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