Nickel-Catalyzed Decarbonylative Thioetherification of Acyl Fluorides via C-F Bond Activation

Nickel-catalyzed decarbonylative thioetherification of acyl fluorides has been developed. This transformation allows an array of acyl fluorides to react with thiophenols. A wide range of functional groups are well tolerated and the corresponding sulfides can be obtained in good to excellent yields. This protocol provides the formation of diverse carbon-sulfur bonds via a highly efficient decarbonylative process.

Automated summary

A nickel-catalyzed decarbonylative thioetherification of acyl fluorides has been developed, allowing a wide range of functional groups to react with thiophenols and obtain corresponding sulfides in good to excellent yields. This protocol provides a highly efficient way to form diverse carbon-sulfur bonds.