Journal
SYNLETT
Volume 32, Issue 10, Pages 1004-1008Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0040-1720461
Keywords
catalysis; heterocycles; cross-coupling; cyclizations; copper
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Funding
- Vietnam National Foundation for Science and Technology Development (NAFOSTED) [104.01-2020.35]
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Two efficient methods for synthesizing beta- and delta-carbolines from 3,4-dibromopyridine are reported, involving Cu-catalyzed double C-N coupling reactions and subsequent Pd-catalyzed C-N coupling with amines.
Two efficient and practical approaches are reported for the synthesis of beta- and delta-carbolines from 3,4-dibromopyridine. The synthesis is based on site-selective Cu-catalyzed double C-N coupling reactions and subsequent annulations by twofold Pd-catalyzed C-N coupling with amines.
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