The Ambibaric Brain Pathophysiological and Clinical Implications

We propose a new evolutionary interpretation of the brain's circulation that has physiological, pathophysiological, and clinical implications. We review the evidence for the concept, discuss clinical implications, and suggest techniques to address outstanding questions. We conclude that the brain circulation contains complementary low-pressure and high-pressure system that must be kept in balance for optimal brain health.

Automated summary

The article introduces a new evolutionary interpretation of the brain's circulation, emphasizing the importance of balancing low-pressure and high-pressure systems for optimal brain health.