Journal
STATISTICS IN MEDICINE
Volume 40, Issue 14, Pages 3367-3384Publisher
WILEY
DOI: 10.1002/sim.8967
Keywords
multiple sclerosis; nonparametrics; win odds; win ratio
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This article discusses the potential difficulties of using the win ratio to compare treatment groups and suggests focusing on the win odds instead. Hypothesis tests and confidence intervals for the win odds are constructed and their properties are investigated through simulations and a case study. It concludes that the win odds should be preferred over the win ratio.
The win ratio, a recently proposed measure for comparing the benefit of two treatment groups, allows ties in the data but ignores ties in the inference. In this article, we highlight some difficulties that this can lead to, and we propose to focus on the win odds instead, a modification of the win ratio which takes ties into account. We construct hypothesis tests and confidence intervals for the win odds, and we investigate their properties through simulations and in a case study. We conclude that the win odds should be preferred over the win ratio.
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