4.3 Article

Biology of Radiation-Induced Lung Injury

Journal

SEMINARS IN RADIATION ONCOLOGY
Volume 31, Issue 2, Pages 155-161

Publisher

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.semradonc.2020.11.006

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Funding

  1. Intramural Research Program of the CCR, NIH

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Radiation-induced lung injury includes radiation pneumonitis, which can be acute or subacute, and radiation-induced lung fibrosis as a late effect of radiation exposure to the lung. This review highlights advancements in molecular radiation biology related to radiation-induced lung injury and their implications in clinical practice.
Radiation-induced lung injury encompasses radiation-induced pneumonitis, inflammation of the lung which may manifest as a dose-limiting acute or subacute toxicity, and radiation-induced lung fibrosis, a late effect of lung exposure to radiation. This review aims to high-light developments in molecular radiation biology of radiation-induced lung injury and their implications in clinical practice Semin Radiat Oncol 31:155-161 Published by Elsevier Inc.

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