Journal
EUROPEAN JOURNAL OF PEDIATRICS
Volume 175, Issue 6, Pages 799-808Publisher
SPRINGER
DOI: 10.1007/s00431-016-2708-8
Keywords
Asthma; Atopic dermatitis; Moderately preterm; Late preterm; Preterm
Categories
Funding
- Pirkanmaa Hospital District [9R051]
- Tampere Tuberculosis Foundation
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This national register study aimed to evaluate the need of asthma medication reimbursement and hospitalization due to asthma and atopic dermatitis up to 7 years of age in moderately preterm (MP) (32-33 weeks) and late preterm (LP) (34-36 weeks) children compared to very preterm (VP) (< 32 weeks) and term (a parts per thousand yen37 weeks) children. Altogether, 1,018,302 children born in Finland between 1991 and 2008 were assessed. The MP and LP groups received asthma medication reimbursement more frequently than term controls (8.0 and 5.7 vs. 3.8 %), but less frequently than VP children (15.4 %). Hospitalization due to asthma was more common among MP (10.6 %) and LP (7.3 %) children than term children (4.8 %) but less common than in VP children (20.1 %). Hospitalization due to atopic dermatitis was more frequent among term (5.2 %) compared to MP (4.2 %) and LP (4.7 %) children. Male sex, maternal smoking, maternal diabetes, and ventilator therapy predicted asthma medication in the MP and/or LP children. Conclusion: MP and LP children seem to need medication and hospitalization for asthma more often than term controls but less frequently than VP children followed by 7 years of age. Hospitalization due to atopic dermatitis becomes more common with increasing gestational age.
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