4.6 Article

Altered Peripersonal Space and the Bodily Self in Schizophrenia: A Virtual Reality Study

Journal

SCHIZOPHRENIA BULLETIN
Volume 47, Issue 4, Pages 927-937

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/schbul/sbab024

Keywords

self-disturbance; multisensory processing; social distance; self-other distinction

Categories

Funding

  1. Gertrude Conaway Vanderbilt Endowment
  2. Vanderbilt Kennedy Center Director's Strategic Grant

Ask authors/readers for more resources

The study found that individuals with schizophrenia have a smaller peripersonal space compared to controls, with increased uncertainty in the self-other boundary in social conditions, leading to heightened false alarms in tactile detection. Clinical symptoms were not clearly associated with peripersonal space parameters.
Self-disturbances such as an anomalous perception of one's own body boundary are central to the phenomenology of schizophrenia (SZ), but measuring the spatial parameters of the hypothesized self-other boundary has proved to be challenging. Peripersonal space (PPS) refers to the immediate zone surrounding the body where the self interacts physically with the environment; the space that corresponds to hypothesized self-other boundary. PPS is represented by enhanced multisensory integration and faster reaction time (RT) for objects near the body. Thus, multisensory RT tasks can be used to estimate self-other boundary. We aimed to quantify PPS in SZ using an immersive virtual reality visuotactile RT paradigm. Twenty-four participants with SZ and 24 demographically matched controls (CO) were asked to detect tactile vibration while watching a ball approaching them, thrown by either a machine (nonsocial condition) or an avatar (social condition). Parameters of PPS were estimated from the midpoint of the spatial range where the tactile RT decreased most rapidly (size) and the gradient of the RT change at this midpoint (slope). Overall, PPS was smaller in participants with SZ compared with CO. PPS slope for participants with SZ was shallower than CO in the social but not in nonsocial condition, indicating an increased uncertainty of self-other boundary across an extended zone in SZ. Social condition also increased false alarms for tactile detection in SZ. Clinical symptoms were not clearly associated with PPS parameters. These findings suggest the context-dependent nature of weakened body boundary in SZ and underscore the importance of reconciliating objective and subjective aspects of self-disturbances.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.6
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available