4.4 Review

Takayasu arteritis in an adolescent with Crohn's disease

Journal

RHEUMATOLOGY INTERNATIONAL
Volume 42, Issue 3, Pages 563-570

Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s00296-021-04869-5

Keywords

Adolescence; Child; Crohn’ s disease; pediatric; Takayasu arteritis; TNF blockers; Vasculitis

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Crohn's disease and Takayasu arteritis are two distinct clinical entities with low likelihood of coexisting. A case of a 15-year-old female initially diagnosed with Crohn's disease and later with Takayasu arteritis is reported. A review of literature showed that in most cases, Crohn's disease was diagnosed first followed by Takayasu arteritis.
Crohn's disease (CD) and Takayasu arteritis (TA) are two distinct clinical entities. tau he likelihood of both diseases coexisting is low, and although CD co-occurs with all types of vasculitis, TA is the most common subtype. Herein, the case of a 15-year-old female, diagnosed with TA following an initial diagnosis of CD, is reported. A review of the literature, including a systemic review of the case reports and case series of children and adolescents up to the age of 21, with both CD and TA, follows the case description. In total, 28 cases of TA and CD were retrieved. The median age of patients was 14.8 years, they were mostly females (72%) and the median time between the two diagnoses was 3.7 years. In the majority of cases, CD was diagnosed first and TA followed. Computed tomography angiography and magnetic resonance angiography were the preferred imaging modalities to assist diagnosis.

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