4.5 Article

Aging versus youth: Endocrine aspects of vulnerability for COVID-19

Related references

Note: Only part of the references are listed.
Article Andrology

Low testosterone levels predict clinical adverse outcomes in SARS-CoV-2 pneumonia patients

Giulia Rastrelli et al.

Summary: In male patients with SARS-CoV-2 pneumonia, lower testosterone levels are associated with poor prognosis and mortality, indicating a potential role for testosterone in determining clinical outcomes in COVID-19 patients.

ANDROLOGY (2021)

Article Immunology

Potential Influence of Menstrual Status and Sex Hormones on Female Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A Cross-sectional Multicenter Study in Wuhan, China

Ting Ding et al.

Summary: Recent studies have shown that female COVID-19 patients have lower morbidity, severe case rate, and mortality compared to males. Nonmenopausal female patients had milder severity and better outcome, while menopausal patients had longer hospitalization times. Anti-Mullerian hormone (AMH) and estradiol (E2) were negatively correlated with COVID-19 severity, with E2 regulating cytokines related to immunity and inflammation.

CLINICAL INFECTIOUS DISEASES (2021)

Review Pharmacology & Pharmacy

Dysregulation of Angiotensin Converting Enzyme 2 Expression and Function in Comorbid Disease Conditions Possibly Contributes to Coronavirus Infectious Disease 2019 Complication Severity

Safaa H. Hammoud et al.

Summary: ACE2 plays a dual role in COVID-19, being protective physiologically while also aiding in viral transmission. The identification of ACE2 in numerous tissues suggests extrapulmonary invasion is likely. Dysregulation of ACE2 in patients with comorbidities may contribute to more severe symptoms.

MOLECULAR PHARMACOLOGY (2021)

Review Clinical Neurology

The COVID-19 Effect on the Immune System and Mitochondrial Dynamics in Diabetes, Obesity, and Dementia

Katherine Holder et al.

Summary: COVID-19 is a pandemic disease caused by SARS-CoV-2, with elderly patients and those with age-related diseases like cardiovascular diseases, diabetes, and obesity being more susceptible to severe respiratory illnesses.

NEUROSCIENTIST (2021)

Review Biotechnology & Applied Microbiology

The role of the thymus in COVID-19 disease severity: implications for antibody treatment and immunization

Caitlyn Kellogg et al.

Summary: The overlooked thymus plays a crucial role in adaptive immune responses, with aging and inflammaging affecting its function and contributing to chronic diseases. Dysfunctional thymus may predispose individuals to severe COVID-19, especially among younger patients with childhood insults to the organ. Monitoring thymic function could aid in COVID-19 care, with treatments targeting thymic regeneration potentially improving overall health outcomes.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2021)

Article Cell Biology

Shorter telomere lengths in patients with severe COVID-19 disease

Raul Sanchez-Vazquez et al.

Summary: Shorter telomeres are associated with increased severity of COVID-19, particularly in older patients. This suggests that molecular pathways related to aging play a role in the disease's progression.

AGING-US (2021)

Article Immunology

Impact of Sex and Metabolic Comorbidities on Coronavirus Disease 2019 (COVID-19) Mortality Risk Across Age Groups: 66 646 Inpatients Across 613 US Hospitals

Katherine E. Goodman et al.

Summary: Men hospitalized with COVID-19 are at increased risk of death across all ages. Hypertension, diabetes with chronic complications, and obesity demonstrated age-dependent effects, with the highest relative risks among adults aged 20-39.

CLINICAL INFECTIOUS DISEASES (2021)

Review Infectious Diseases

COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection

Stephany Beyerstedt et al.

Summary: ACE2 plays a crucial role in COVID-19, with its expression potentially having paradoxical effects, aiding SARS-CoV-2 pathogenicity while also limiting viral infection.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2021)

Article Immunology

ACE2 and TMPRSS2 polymorphisms in various diseases with special reference to its impact on COVID-19 disease

HariOm Singh et al.

Summary: The ACE2 and TMPRSS2 genes play crucial roles in diseases such as COVID-19, with their polymorphisms linked to infection severity. Population-specific variations in these genes could influence the severity of viral infections in different demographic groups.

MICROBIAL PATHOGENESIS (2021)

Review Endocrinology & Metabolism

Visceral Adiposity Elevates the Risk of Critical Condition in COVID-19: A Systematic Review and Meta-Analysis

Maria Foldi et al.

Summary: This study found that patients with critical condition in COVID-19, including those requiring intensive care and invasive mechanical ventilation, had significantly higher visceral fat area (VFA) values. Therefore, abdominal adiposity appears to be a risk factor in COVID-19, and patients with central obesity may require special attention.

OBESITY (2021)

Article Endocrinology & Metabolism

Visceral adipose tissue area predicts intensive care unit admission in COVID-19 patients

Federica Pediconi et al.

Summary: A retrospective study of 62 hospitalized COVID-19 patients found that CT-derived visceral adipose tissue score was the best predictor for ICU admission, while the analysis of pre-existing comorbidities was not relevant.

OBESITY RESEARCH & CLINICAL PRACTICE (2021)

Article Endocrinology & Metabolism

Visceral fat is associated to the severity of COVID-19

Guillaume Favre et al.

Summary: The study found that visceral fat accumulation is associated with severe COVID-19 in European adults, while subcutaneous fat is not. An area of visceral fat greater than or equal to 128.5 cm(2) was identified as the best predictor for severe COVID-19.

METABOLISM-CLINICAL AND EXPERIMENTAL (2021)

Review Microbiology

Comorbidities in SARS-CoV-2 Patients: a Systematic Review and Meta-Analysis

Wern Hann Ng et al.

Summary: Hypertension, obesity, and diabetes mellitus are the most prevalent comorbidities in COVID-19 patients, while chronic kidney disease stands out as the most prominent factor leading to death. However, despite its high prevalence, obesity is not associated with mortality in COVID-19 patients.
Article Nutrition & Dietetics

Sarcopenia: An underlying treatment target during the COVID-19 pandemic

Pei-yu Wang et al.

Summary: The role of skeletal muscle mass in modulating immune response and metabolic stress is crucial. Patients with sarcopenia have poor immune response and metabolic stress, leading to increased infection rates and worsened prognosis during the COVID-19 epidemic. Interventions targeting skeletal muscle are essential to break the vicious circle and benefit the treatment of both conditions.

NUTRITION (2021)

Review Endocrinology & Metabolism

Hypovitaminosis D and the endocrine phenotype of COVID-19

Andrea Giustina

Summary: The review suggests that there may be an endocrine phenotype related to COVID-19, with a correlation between 25 hydroxyvitamin D levels and different clinical outcomes of the disease. Therefore, various endocrine manifestations of COVID-19 could potentially be explained in the context of inadequate vitamin D status.

ENDOCRINE (2021)

Article Obstetrics & Gynecology

Change in Covid-19 infection and mortality rates in postmenopausal women

Angelo Cagnacci et al.

Summary: The study found opposing trends in COVID-19 infection and death rates among women of different age groups. Specifically, women aged 20 to 59 had higher infection rates but lower mortality rates compared to men, while women aged 60 to 89 had lower infection rates but higher mortality rates.

MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (2021)

Article Cell & Tissue Engineering

An Assessment on Impact of COVID-19 Infection in a Gender Specific Manner

Himanshu Agrawal et al.

Summary: COVID-19 is caused by the novel coronavirus SARS-CoV-2, leading to severe infections that result in multi-organ damage and respiratory failure. While specific treatment and vaccines are lacking, studies have shown that certain individuals such as those with hypertension, diabetes, cardiovascular diseases, and male patients are at higher risk of infection and mortality.

STEM CELL REVIEWS AND REPORTS (2021)

Article Geriatrics & Gerontology

Comparing EWGSOP2 and FNIH Sarcopenia Definitions: Agreement and 3-Year Survival Prognostic Value in Older Hospitalized Adults: The GLISTEN Study

Lara Bianchi et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2020)

Article Geriatrics & Gerontology

Longitudinal Change in Cortisol Levels Across the Adult Life Span

Scott D. Moffat et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2020)

Review Cardiac & Cardiovascular Systems

Mechanisms of Vascular Aging, A Geroscience Perspective JACC Focus Seminar

Zoltan Ungvari et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2020)

Article Multidisciplinary Sciences

Sexual-dimorphism in human immune system aging

Eladio J. Marquez et al.

NATURE COMMUNICATIONS (2020)

Article Biochemistry & Molecular Biology

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

Daniel Blanco-Melo et al.

Article Microbiology

Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure

Evangelos J. Giamarellos-Bourboulis et al.

CELL HOST & MICROBE (2020)

Article Immunology

Age-dependent Gender Differences in COVID-19 in Mainland China: Comparative Study

Jie Qian et al.

CLINICAL INFECTIOUS DISEASES (2020)

Letter Medicine, General & Internal

Endothelial cell infection and endotheliitis in COVID-19

Zsuzsanna Varga et al.

LANCET (2020)

Editorial Material Multidisciplinary Sciences

Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients

Yonggang Zhou et al.

NATIONAL SCIENCE REVIEW (2020)

Article Biochemistry & Molecular Biology

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

Mingfeng Liao et al.

NATURE MEDICINE (2020)

Editorial Material Geriatrics & Gerontology

COVID-19: a major cause of cachexia and sarcopenia?

John E. Morley et al.

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2020)

Review Infectious Diseases

Does gender influence clinical expression and disease outcomes in COVID-19? A systematic review and meta-analysis

Augusta Ortolan et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2020)

Article Immunology

The Lung Macrophage in SARS-CoV-2 Infection: A Friend or a Foe?

Zaid Abassi et al.

FRONTIERS IN IMMUNOLOGY (2020)

Review Immunology

Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies

Yujun Tang et al.

FRONTIERS IN IMMUNOLOGY (2020)

Review Endocrinology & Metabolism

Hypercoagulopathy and Adipose Tissue Exacerbated Inflammation May Explain Higher Mortality in COVID-19 Patients With Obesity

Gabriel Pasquarelli-do-Nascimento et al.

FRONTIERS IN ENDOCRINOLOGY (2020)

Review Geriatrics & Gerontology

Severe COVID-19 and aging: are monocytes the key?

Brandt D. Pence

GEROSCIENCE (2020)

Review Cell Biology

Type I interferons and related pathways in cell senescence

Steven M. Frisch et al.

AGING CELL (2020)

Review Cell Biology

B Cell Immunosenescence

Daniela Frasca et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 36, 2020 (2020)

Review Hematology

Coagulopathy in COVID-19

Toshiaki Iba et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2020)

Article Endocrinology & Metabolism

Visceral fat shows the strongest association with the need of intensive care in patients with COVID-19

Mikiko Watanabe et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2020)

Article Multidisciplinary Sciences

Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients

Jerome Hadjadj et al.

SCIENCE (2020)

Article Radiology, Nuclear Medicine & Medical Imaging

The prognostic value of pneumonia severity score and pectoralis muscle Area on chest CT in adult COVID-19 patients

Furkan Ufuk et al.

EUROPEAN JOURNAL OF RADIOLOGY (2020)

Article Cell Biology

A human circulating immune cell landscape in aging and COVID-19

Yingfeng Zheng et al.

PROTEIN & CELL (2020)

Article Medicine, Research & Experimental

COVID-19 severity associates with pulmonary redistribution of CD1c+ DCs and inflammatory transitional and nonclassical monocytes

Ildefonso Sanchez-Cerrillo et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

Article Medicine, General & Internal

Sex and gender: modifiers of health, disease, and medicine

Franck Mauvais-Jarvis et al.

LANCET (2020)

Article Endocrinology & Metabolism

The role of visceral adiposity in the severity of COVID-19: Highlights from a unicenter cross-sectional pilot study in Germany

Antonia Petersen et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2020)

Review Cell Biology

Mitochondria and microbiota dysfunction in COVID-19 pathogenesis

Jumana Saleh et al.

MITOCHONDRION (2020)

Article Multidisciplinary Sciences

Sex differences in immune responses that underlie COVID-19 disease outcomes

Takehiro Takahashi et al.

NATURE (2020)

Article Biochemistry & Molecular Biology

An inflammatory cytokine signature predicts COVID-19 severity and survival

Diane Marie Del Valle et al.

NATURE MEDICINE (2020)

Article Multidisciplinary Sciences

Who is wearing a mask? Gender-, age-, and location-related differences during the COVID-19 pandemic

Michael H. Haischer et al.

PLOS ONE (2020)

Review Immunology

Immunosenescence is both functional/adaptive and dysfunctional/maladaptive

T. Fulop et al.

SEMINARS IN IMMUNOPATHOLOGY (2020)

Review Endocrinology & Metabolism

Sexual Dimorphism of Coronavirus 19 Morbidity and Lethality

Maria Luisa Brandi et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2020)

Article Physiology

Regulation of Angiotensin- Converting Enzyme 2 in Obesity: Implications for COVID-19

Saba Al Heialy et al.

FRONTIERS IN PHYSIOLOGY (2020)

Editorial Material Endocrinology & Metabolism

Obesity and COVID-19

Domenico Azzolino et al.

FRONTIERS IN ENDOCRINOLOGY (2020)

Review Cell Biology

Insights on SARS-CoV-2 Molecular Interactions With the Renin-Angiotensin System

Larissa Braga Costa et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)

Article Medicine, General & Internal

Evidence for treatment with estradiol for women with SARS-CoV-2 infection

Ute Seeland et al.

BMC MEDICINE (2020)

Article Multidisciplinary Sciences

Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission

Hannah Peckham et al.

NATURE COMMUNICATIONS (2020)

Article Cell Biology

Short telomeres increase the risk of severe COVID-19

Antoine Froidure et al.

AGING-US (2020)

Article Geriatrics & Gerontology

Post-COVID-19 global health strategies: the need for an interdisciplinary approach

AGING CLINICAL AND EXPERIMENTAL RESEARCH (2020)

Article Immunology

Considering how biological sex impacts immune responses and COVID-19 outcomes

Eileen P. Scully et al.

NATURE REVIEWS IMMUNOLOGY (2020)

Review Immunology

Macrophage activation syndrome and COVID-19

Ryo Otsuka et al.

INFLAMMATION AND REGENERATION (2020)

Article Immunology

T cell responses in patients with COVID-19

Zeyu Chen et al.

NATURE REVIEWS IMMUNOLOGY (2020)

Article Geriatrics & Gerontology

Sarcopenia: revised European consensus on definition and diagnosis

Alfonso J. Cruz-Jentoft et al.

AGE AND AGEING (2019)

Article Endocrinology & Metabolism

Urinary Sex Steroid and Glucocorticoid Hormones Are Associated With Muscle Mass and Strength in Healthy Adults

Murielle Bochud et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2019)

Review Obstetrics & Gynecology

Fat mass changes during menopause: a metaanalysis

Ananthan Ambikairajah et al.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2019)

Article Geriatrics & Gerontology

Risk of community-acquired pneumonia in older adults with sarcopenia of a hospital from Callao, Peru 2010-2015

Sofia Altuna-Venegas et al.

ARCHIVES OF GERONTOLOGY AND GERIATRICS (2019)

Article Pathology

Diversity, Mechanisms, and Significance of Macrophage Plasticity

Massimo Locati et al.

Annual Review of Pathology-Mechanisms of Disease (2019)

Article Endocrinology & Metabolism

Thigh and abdominal adipose tissue depot associations with testosterone levels in postmenopausal females

Emmanuel K. Ofori et al.

CLINICAL ENDOCRINOLOGY (2019)

Review Endocrinology & Metabolism

Skeletal and Extraskeletal Actions of Vitamin D: Current Evidence and Outstanding Questions

Roger Bouillon et al.

ENDOCRINE REVIEWS (2019)

Review Immunology

Sex and sex steroids impact influenza pathogenesis across the life course

Landon G. vom Steeg et al.

SEMINARS IN IMMUNOPATHOLOGY (2019)

Review Cell Biology

Telomere Biology and Human Phenotype

Kara J. Turner et al.

CELLS (2019)

Review Immunology

B Cell Dysfunction Associated With Aging and Autoimmune Diseases

Shiliang Ma et al.

FRONTIERS IN IMMUNOLOGY (2019)

Article Geriatrics & Gerontology

Failed Recovery of Glycemic Control and Myofibrillar Protein Synthesis With 2 wk of Physical Inactivity in Overweight, Prediabetic Older Adults

Chris McGlory et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2018)

Article Physiology

Attenuation of pulmonary ACE2 activity impairs inactivation of des-Arg(9) bradykinin/BKB1R axis and facilitates LPS-induced neutrophil infiltration

Chhinder P. Sodhi et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2018)

Article Geriatrics & Gerontology

Reduced dynamic range of antiviral innate immune responses in aging

Ryan D. Molony et al.

EXPERIMENTAL GERONTOLOGY (2018)

Article Endocrinology & Metabolism

High Androgens in Postmenopausal Women and the Risk for Atherosclerosis and Cardiovascular Disease: The Rotterdam Study

Cindy Meun et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2018)

Article Cell Biology

Interleukin 6 inhibits the differentiation of rat stem Leydig cells

Yiyan Wang et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2018)

Review Cardiac & Cardiovascular Systems

Endothelial dysfunction and angiogenesis impairment in the ageing vasculature

Zoltan Ungvari et al.

NATURE REVIEWS CARDIOLOGY (2018)

Review Geriatrics & Gerontology

Acute Sarcopenia Secondary to Hospitalisation - An Emerging Condition Affecting Older Adults

Carly Welch et al.

AGING AND DISEASE (2018)

Review Immunology

The twilight of immunity: emerging concepts in aging of the immune system

Janko Nikolich-Zugich

NATURE IMMUNOLOGY (2018)

Review Endocrinology & Metabolism

Inflammaging and 'Garb-aging'

Claudio Franceschi et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2017)

Article Geriatrics & Gerontology

The incidence of sarcopenia among hospitalized older patients: results from the Glisten study

Anna Maria Martone et al.

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2017)

Article Physiology

The Role of Inflammation in Age-Related Sarcopenia

Sebastiaan Dalle et al.

FRONTIERS IN PHYSIOLOGY (2017)

Review Geriatrics & Gerontology

The Role of Ghrelin in Senescence: A Mini-Review

Yue Yin et al.

GERONTOLOGY (2016)

Review Public, Environmental & Occupational Health

Clinical determinants of the severity of Middle East respiratory syndrome (MERS): a systematic review and meta-analysis

Ryota Matsuyama et al.

BMC PUBLIC HEALTH (2016)

Review Neurosciences

Integrating neuroimmune systems in the neurobiology of depression

Eric S. Wohleb et al.

NATURE REVIEWS NEUROSCIENCE (2016)

Article Multidisciplinary Sciences

Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease

Padmini S. Pillai et al.

SCIENCE (2016)

Article Multidisciplinary Sciences

Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis

Megan K. Ruhland et al.

NATURE COMMUNICATIONS (2016)

Article Microbiology

SeXX Matters in Infectious Disease Pathogenesis

Landon G. vom Steeg et al.

PLOS PATHOGENS (2016)

Article Physiology

Neuroendocrine Regulation of Growth Hormone Secretion

Frederik J. Steyn et al.

COMPREHENSIVE PHYSIOLOGY (2016)

Review Immunology

Sex differences in immune responses

Sabra L. Klein et al.

NATURE REVIEWS IMMUNOLOGY (2016)

Article Immunology

Somatotrope GHRH/GH/IGF-1 axis at the crossroads between immunosenescence and frailty

Gwennaelle Bodart et al.

NEUROIMMUNOMODULATION IN HEALTH AND DISEASE (2015)

Article Endocrinology & Metabolism

Associations Between Sex Steroids and the Development of Metabolic Syndrome: A Longitudinal Study in European Men

Leen Antonio et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2015)

Review Biochemistry & Molecular Biology

Cellular senescence in aging and age-related disease: from mechanisms to therapy

Bennett G. Childs et al.

NATURE MEDICINE (2015)

Review Physiology

Sex and Gender Impact Immune Responses to Vaccines Among the Elderly

Ashley L. Fink et al.

PHYSIOLOGY (2015)

Article Endocrinology & Metabolism

EFFECTS OF TRANSDERMAL TESTOSTERONE TREATMENT ON INFLAMMATORY MARKERS IN ELDERLY MALES

Marcello Maggio et al.

ENDOCRINE PRACTICE (2014)

Review Cell Biology

Mechanisms and Metabolic Implications of Regional Differences among Fat Depots

Tamara Tchkonia et al.

CELL METABOLISM (2013)

Article Nutrition & Dietetics

Sarcopenia: Prevalence and prognostic significance in hospitalized patients

Salah Gariballa et al.

CLINICAL NUTRITION (2013)

Article Endocrinology & Metabolism

Two Weeks of Reduced Activity Decreases Leg Lean Mass and Induces Anabolic Resistance of Myofibrillar Protein Synthesis in Healthy Elderly

Leigh Breen et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2013)

Letter Medicine, General & Internal

Gonadal Steroids and Body Composition, Strength, and Sexual Function in Men

Joel S. Finkelstein et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Multidisciplinary Sciences

Increased Skeletal Muscle 11βHSD1 mRNA Is Associated with Lower Muscle Strength in Ageing

Alixe H. M. Kilgour et al.

PLOS ONE (2013)

Article Medicine, General & Internal

Gonadal Steroids and Body Composition, Strength, and Sexual Function in Men

Joel S. Finkelstein et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Endocrinology & Metabolism

Characteristics of Androgen Deficiency in Late-Onset Hypogonadism: Results from the European Male Aging Study (EMAS)

Abdelouahid Tajar et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)

Review Cell Biology

Mechanisms of sex disparities in influenza pathogenesis

Sabra L. Klein et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2012)

Article Endocrinology & Metabolism

Ageing, physical function, and the diurnal rhythms of cortisol and dehydroepiandrosterone

Jennifer L. J. Heaney et al.

PSYCHONEUROENDOCRINOLOGY (2012)

Article Endocrinology & Metabolism

Higher Serum Testosterone Concentration in Older Women is Associated with Insulin Resistance, Metabolic Syndrome, and Cardiovascular Disease

Shrita M. Patel et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)

Article Endocrinology & Metabolism

Low serum testosterone and mortality in older men

Gail A. Laughlin et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)

Article Endocrinology & Metabolism

Hypothalamic-pituitary-testicular axis disruptions in older men are differentially linked to age and modifiable risk factors: The European Male Aging Study

Frederick C. W. Wu et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)

Article Endocrinology & Metabolism

Anatomical patterning of visceral adipose tissue: Race, sex, and age variation

Ellen W. Demerath et al.

OBESITY (2007)

Review Biochemistry & Molecular Biology

Toll-like receptors and type I interferons

Satoshi Uematsu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Letter Medicine, General & Internal

Effect of 10 days of bed rest on skeletal muscle in healthy older adults

Patrick Kortebein et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2007)

Article Medicine, General & Internal

DHEA in elderly women and DHEA or testosterone in elderly men

K. Sreekumaran Nair et al.

NEW ENGLAND JOURNAL OF MEDICINE (2006)

Article Medicine, Research & Experimental

Age- and gender-related difference of ACE2 expression in rat lung

XD Xie et al.

LIFE SCIENCES (2006)

Article Nutrition & Dietetics

Weight change and the conservation of lean mass in old age: the Health, Aging and Body Composition Study

AB Newman et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2005)

Article Multidisciplinary Sciences

Angiotensin-converting enzyme 2 protects from severe acute lung failure

Y Imai et al.

NATURE (2005)

Article Public, Environmental & Occupational Health

Do men have a higher case fatality rate of severe acute respiratory syndrome than women do?

J Karlberg et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2004)

Article Endocrinology & Metabolism

The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men

CJ Malkin et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)

Article Endocrinology & Metabolism

The metabolic syndrome in obese postmenopausal women: Relationship to body composition, visceral fat, and inflammation

TJ You et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)

Article Immunology

Immunity to influenza - The challenges of protecting an aging population

JM Katz et al.

IMMUNOLOGIC RESEARCH (2004)

Review Immunology

Immunosenescence and infectious diseases

L Ginaldi et al.

MICROBES AND INFECTION (2001)

Article Biochemistry & Molecular Biology

A human homolog of angiotensin-converting enzyme - Cloning and functional expression as a captopril-insensitive carboxypeptidase

SR Tipnis et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)

Article Cardiac & Cardiovascular Systems

A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9

M Donoghue et al.

CIRCULATION RESEARCH (2000)