Preparation of bactericidal surfaces with high quaternary ammonium content through photo-initiated polymerization of N-[2-(acryloyloxy) ethyl]-N,N-dimethyl-N-butylammonium iodide from native and thiolated PDMS surfaces

N-[2-(acryloyloxy)ethyl]-N,N-dimethyl-N-butylammonium iodide was successfully photo-polymerized from native and thiolated PDMS surface, in the presence of benzophenone. The directly and indirectly grafted surfaces exhibited quaternary ammonium densities of about 1015 and 1017 N+.cm 2, respectively, and very high hydrophilicity compared to non-grafted surfaces. The live and dead tests performed by fluorescence microscopy revealed an effective contact bactericidal effect of this surface against Escherichia coli and Staphylococcus epidermidis.

Automated summary

The successful photo-polymerization of N-[2-(acryloyloxy)ethyl]-N,N-dimethyl-N-butylammonium iodide from native and thiolated PDMS surface, in the presence of benzophenone, resulted in highly hydrophilic surfaces with effective bactericidal effects against Escherichia coli and Staphylococcus epidermidis.