4.5 Article

Cross Dehydrogenative Coupling (CDC) Reactions of N,N-Disubstituted Formamides, Benzaldehydes and Cycloalkanes

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2016, Issue 29, Pages 4927-4947

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201600401

Keywords

C-H activation; C-C coupling; C-X coupling; Cross coupling; Dehydrogenation; Peroxides; Radical reactions

Funding

  1. Council of Scientific and Industrial Research (CSIR), New Delhi [02(0131)/13/EMR-II]

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In recent years, reactions of inexpensive and easily available formamides, benzaldehydes and cycloalkanes with various coupling partners have made an impact in the field of cross dehydrogenative coupling. Even in the absence of a benzylic C-H site or a heteroatom at the a-position, these substrates react efficiently under oxidative conditions. This review article highlights recent advances in cross dehydrogenative coupling reactions for C-C and C-heteroatom bond formation with the above substrates.

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