Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2016, Issue 18, Pages 3119-3125Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201600545
Keywords
Glycosides; Glycosyl bromide; Halogens; Promoters; Synthetic methods
Categories
Funding
- Danish Council for Independent Research/Natural Sciences
Ask authors/readers for more resources
Iodonium ions have been developed for activating glycosyl bromides in the coupling to glycosyl acceptors. The iodonium ions are generated from N-iodosuccinimide and a protic acid such as camphorsulfonic acid or triflic acid, where the latter gives the most reactive promoter system. The couplings occur with the release of iodine monobromide, and the best results are obtained with benzoylated glycosyl donors and acceptors. In this way, disarmed glycosyl bromides can serve as glycosyl donors without the use of heavy-metal salts.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available