4.6 Article

High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV-2 nsp15 endoribonuclease to identify small-molecule inhibitors of viral activity

Related references

Note: Only part of the references are listed.
Article Physics, Atomic, Molecular & Chemical

Native mass spectrometry reveals the simultaneous binding of lipids and zinc to rhodopsin

Carolanne E. Norris et al.

Summary: This study revealed that phosphatidylcholine binds to rhodopsin with a greater affinity than other phospholipids, and all lipid bindings are influenced by zinc but with different effects. In contrast, zinc binding is relatively unaffected by lipids.

INTERNATIONAL JOURNAL OF MASS SPECTROMETRY (2021)

Article Multidisciplinary Sciences

A new coronavirus associated with human respiratory disease in China

Fan Wu et al.

NATURE (2020)

Article Multidisciplinary Sciences

Coronavirus endoribonuclease targets viral polyuridine sequences to evade activating host sensors

Matthew Hackbart et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Biochemistry & Molecular Biology

Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV-2

Youngchang Kim et al.

PROTEIN SCIENCE (2020)

Article Multidisciplinary Sciences

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

David E. Gordon et al.

NATURE (2020)

Article Multidisciplinary Sciences

Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors

Zhenming Jin et al.

NATURE (2020)

Article Chemistry, Analytical

Simple and Minimally Invasive SID Devices for Native Mass Spectrometry

Dalton T. Snyder et al.

ANALYTICAL CHEMISTRY (2020)

Article Chemistry, Multidisciplinary

Allosteric Inhibition of the SARS-CoV-2 Main Protease: Insights from Mass Spectrometry Based Assays

Tarick J. El-Baba et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Cell Biology

Evasion of Type I Interferon by SARS-CoV-2

Hongjie Xia et al.

CELL REPORTS (2020)

Article Chemistry, Medicinal

Ebselen, Disulfiram, Carmofur, PX-12, Tideglusib, and Shikonin Are Nonspecific Promiscuous SARS-CoV-2 Main Protease Inhibitors

Chunlong Ma et al.

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (2020)

Review Chemistry, Analytical

Surface-Induced Dissociation: An Effective Method for Characterization of Protein Quaternary Structure

Alyssa Q. Stiving et al.

ANALYTICAL CHEMISTRY (2019)

Article Multidisciplinary Sciences

The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis

Jeff Janes et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Computer Science, Hardware & Architecture

Application performance analysis and efficient execution on systems with multi-core CPUs, GPUs and MICs: a case study with microscopy image analysis

George Teodoro et al.

INTERNATIONAL JOURNAL OF HIGH PERFORMANCE COMPUTING APPLICATIONS (2017)

Article Multidisciplinary Sciences

Coronavirus nonstructural protein 15 mediates evasion of dsRNA sensors and limits apoptosis in macrophages

Xufang Deng et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Protein-Ligand Blind Docking Using QuickVina-W With Inter-Process Spatio-Temporal Integration

Nafisa M. Hassan et al.

SCIENTIFIC REPORTS (2017)

Article Biochemical Research Methods

Fast, accurate, and reliable molecular docking with QuickVina 2

Amr Alhossary et al.

BIOINFORMATICS (2015)

Article Multidisciplinary Sciences

Antibacterial drug leads targeting isoprenoid biosynthesis

Wei Zhu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Biochemical Research Methods

Immobilized metal-affinity chromatography protein-recovery screening is predictive of crystallographic structure success

Ryan Choi et al.

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS (2011)

Article Chemistry, Multidisciplinary

Open Babel: An open chemical toolbox

Noel M. O'Boyle et al.

JOURNAL OF CHEMINFORMATICS (2011)

Article Biochemistry & Molecular Biology

Structural and functional analyses of the severe acute respiratory syndrome coronavirus endoribonuclease Nsp15

Kanchan Bhardwaj et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biotechnology & Applied Microbiology

Suppressing posttranslational gluconoylation of heterologous proteins by metabolic engineering of Escherichia coli

Juan C. Aon et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2008)

Article Multidisciplinary Sciences

The structure of the endoribonuclease XendoU: From small nucleolar RNA processing to severe acute respiratory syndrome coronavirus replication

Fabiana Renzi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Multidisciplinary Sciences

Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family

Stefano Ricagno et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemical Research Methods

Protein production by auto-induction in high-density shaking cultures

FW Studier

PROTEIN EXPRESSION AND PURIFICATION (2005)

Article Multidisciplinary Sciences

Major genetic marker of nidoviruses encodes a replicative endoribonuclease

KA Ivanov et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)