Journal
PHYSIOLOGY
Volume 36, Issue 3, Pages 160-173Publisher
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00036.2020
Keywords
angiotensin receptor blockers; COVID-19; estrogen; inflammation; neuroprotection
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In addition to controlling blood pressure, angiotensin receptor blockers also reduce inflammation and protect various organ functions, making them useful in treating inflammatory, age-related, neurodegenerative, and metabolic disorders.
Beyond blood pressure control, angiotensin receptor blockers reduce common injury mechanisms, decreasing excessive inflammation and protecting endothelial and mitochondrial function, insulin sensitivity, the coagulation cascade, immune responses, cerebrovascular flow, and cognition, properties useful to treat inflammatory, age-related, neurodegenerative, and metabolic disorders of many organs including brain and lung.
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