4.4 Article

Surgery with emicizumab prophylaxis for two paediatric patients with severe haemophilia A with inhibitors

Related references

Note: Only part of the references are listed.
Article Hematology

Comparison of bypassing agents in patients on emicizumab using global hemostasis assays

Hande Kizilocak et al.

Summary: The study found that adding BPA to plasma from patients on emicizumab increased thrombin generation, and licensed doses of aPCC led to excessive thrombin generation. Thromboelastography was not sensitive enough. Clinical studies are needed to confirm the safety of using lower doses of aPCC with emicizumab.

HAEMOPHILIA (2021)

Review Chemistry, Medicinal

Clinical Evidence and Safety Profile of Emicizumab for the Management of Children with Hemophilia A

Sandra Le Quellec

DRUG DESIGN DEVELOPMENT AND THERAPY (2020)

Article Hematology

Emicizumab treatment and monitoring in a paediatric cohort: real-world data

Assaf A. Barg et al.

BRITISH JOURNAL OF HAEMATOLOGY (2020)

Article Pharmacology & Pharmacy

Emicizumab-kxwh: First Global Approval

Lesley J. Scott et al.

DRUGS (2018)

Article Hematology

In vitro studies show synergistic effects of a procoagulant bispecific antibody and bypassing agents

R. Hartmann et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2018)

Article Medicine, General & Internal

Emicizumab Prophylaxis in Patients Who Have Hemophilia A without Inhibitors

J. Mahlangu et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Medicine, General & Internal

Emicizumab Prophylaxis in Hemophilia A with Inhibitors

Johannes Oldenburg et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Hematology

Bispecific antibody mimicking factor VIII

Keiji Nogami

THROMBOSIS RESEARCH (2016)

Review Hematology

Factor VIII therapy for hemophilia A: current and future issues

Louis Aledort et al.

EXPERT REVIEW OF HEMATOLOGY (2014)

Review Hematology

Mechanisms and monitoring of bypassing agent therapy

M. Hoffman et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2012)

Review Hematology

Treatment of hemophilia: a review of current advances and ongoing issues

Antonio Coppola et al.

JOURNAL OF BLOOD MEDICINE (2010)

Review Hematology

The measurement and application of thrombin generation

T Baglin

BRITISH JOURNAL OF HAEMATOLOGY (2005)

Review Hematology

Inhibitors in congenital coagulation disorders

NS Key

BRITISH JOURNAL OF HAEMATOLOGY (2004)

Review Medicine, General & Internal

Medical progress - The hemophilias - From royal genes to gene therapy

PM Mannucci et al.

NEW ENGLAND JOURNAL OF MEDICINE (2001)