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Monoclonal Gammopathy of Renal Significance

Journal

NEW ENGLAND JOURNAL OF MEDICINE
Volume 384, Issue 20, Pages 1931-1941

Publisher

MASSACHUSETTS MEDICAL SOC
DOI: 10.1056/NEJMra1810907

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Monoclonal gammopathy of renal significance is a non-cancerous clonal disorder that produces monoclonal immunoglobulin leading to kidney injury or disease. It is discussed in terms of pathogenesis, evaluation, and management.
Monoclonal Gammopathy of Renal Significance Monoclonal gammopathy of renal significance is a B-cell or plasma-cell clonal disorder that does not meet the criteria for cancer but produces a monoclonal immunoglobulin that leads to kidney injury or disease. This review discusses pathogenesis, evaluation, and management.

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