Human cells and networks of pain Transforming pain target identification and therapeutic development

Chronic pain is a disabling disease with limited treatment options. While animal models have revealed important aspects of pain neurobiology, therapeutic translation of this knowledge requires our understanding of these cells and networks of pain in humans. We propose a multi-institutional collaboration to rigorously and ethically address this challenge.

Automated summary

Chronic pain is a debilitating disease with limited treatment options. Understanding pain cells and networks in humans is crucial for translating knowledge from animal models to therapeutic applications. A multi-institutional collaboration is proposed to address this challenge rigorously and ethically.