Journal
NEURON
Volume 109, Issue 10, Pages 1585-1587Publisher
CELL PRESS
DOI: 10.1016/j.neuron.2021.04.022
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The study identified the RNAs sequestered by tau inclusions and showed related perturbations in nuclear speckles.
Protein aggregates can sequester RNA in neurodegenerative disease, but the exact RNAs sequestered by tau inclusions have remained uncharacterized. In this issue of Neuron, Lester et al. (2021) begin to identify these RNAs and reveal related perturbations in nuclear speckles.
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