Related references
Note: Only part of the references are listed.The search for brain-permeant NKCC1 inhibitors for the treatment of seizures: Pharmacokinetic-pharmacodynamic modelling of NKCC1 inhibition by azosemide, torasemide, and bumetanide in mouse brain
Philip Hampel et al.
EPILEPSY & BEHAVIOR (2021)
Impaired chloride homeostasis in epilepsy: Molecular basis, impact on treatment, and current treatment approaches
Theresa Auer et al.
PHARMACOLOGY & THERAPEUTICS (2020)
Proof-of-concept that network pharmacology is effective to modify development of acquired temporal lobe epilepsy
Alina Schidlitzki et al.
NEUROBIOLOGY OF DISEASE (2020)
Role of NKCC1 and KCC2 in Epilepsy: From Expression to Function
Ru Liu et al.
FRONTIERS IN NEUROLOGY (2020)
NKCC1, an Elusive Molecular Target in Brain Development: Making Sense of the Existing Data
Mari A. Virtanen et al.
CELLS (2020)
The signaling role for chloride in the bidirectional communication between neurons and astrocytes
Corinne S. Wilson et al.
NEUROSCIENCE LETTERS (2019)
Transient use of a systemic adenosine kinase inhibitor attenuates epilepsy development in mice
Ursula S. Sandau et al.
EPILEPSIA (2019)
Off-Label Use of Bumetanide for Brain Disorders: An Overview
Shivani C. Kharod et al.
FRONTIERS IN NEUROSCIENCE (2019)
Moving beyond P values: data analysis with estimation graphics
Joses Ho et al.
NATURE METHODS (2019)
Understanding Tendons: Lessons from Transgenic Mouse Models
Manuel Delgado Caceres et al.
STEM CELLS AND DEVELOPMENT (2018)
Bumepamine, a brain-permeant benzylamine derivative of bumetanide, does not inhibit NKCC1 but is more potent to enhance phenobarbital's anti seizure efficacy
Claudia Brandt et al.
NEUROPHARMACOLOGY (2018)
A Mesiotemporal Lobe Epilepsy Mouse Model
Duveau Venceslas et al.
NEUROCHEMICAL RESEARCH (2017)
NKCC1Chloride Importer Antagonists Attenuate Many Neurological and Psychiatric Disorders
Yehezkel Ben-Ari
TRENDS IN NEUROSCIENCES (2017)
A combination of NMDA and AMPA receptor antagonists retards granule cell dispersion and epileptogenesis in a model of acquired epilepsy
Alina Schidlitzki et al.
SCIENTIFIC REPORTS (2017)
Depolarizing -aminobutyric acid contributes to glutamatergic network rewiring in epilepsy
Nazim Kourdougli et al.
ANNALS OF NEUROLOGY (2017)
Bumetanide reduces seizure progression and the development of pharmacoresistant status epilepticus
Sudhir Sivakumaran et al.
EPILEPSIA (2016)
Differential Effects of Antiepileptic Drugs on Focal Seizures in the Intrahippocampal Kainate Mouse Model of Mesial Temporal Lobe Epilepsy
Venceslas Duveau et al.
CNS NEUROSCIENCE & THERAPEUTICS (2016)
Significant effects of sex, strain, and anesthesia in the intrahippocampal kainate mouse model of mesial temporal lobe epilepsy
Friederike Twele et al.
EPILEPSY & BEHAVIOR (2016)
Activation of GABAA receptors controls mesiotemporal lobe epilepsy despite changes in chloride transporters expression: In vivo and in silico approach
Severine Stamboulian-Platel et al.
EXPERIMENTAL NEUROLOGY (2016)
Brain inflammation, neurodegeneration and seizure development following picornavirus infection markedly differ among virus and mouse strains and substrains
Sonja Broeer et al.
EXPERIMENTAL NEUROLOGY (2016)
Age- and sex-dependent susceptibility to phenobarbital-resistant neonatal seizures: role of chloride co-transporters
Seok Kyu Kang et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2015)
A Novel Prodrug-Based Strategy to Increase Effects of Bumetanide in Epilepsy
Kathrin Toellner et al.
ANNALS OF NEUROLOGY (2014)
GABA actions and ionic plasticity in epilepsy
Kai Kaila et al.
CURRENT OPINION IN NEUROBIOLOGY (2014)
Pharmacotherapeutic targeting of cation-chloride cotransporters in neonatal seizures
Martin Puskarjov et al.
EPILEPSIA (2014)
NIH to balance sex in cell and animal studies
Janine A. Clayton et al.
NATURE (2014)
Cation-chloride cotransporters in neuronal development, plasticity and disease
Kai Kaila et al.
NATURE REVIEWS NEUROSCIENCE (2014)
Physiology and pathophysiology of SLC12A1/2 transporters
Nicolas Markadieu et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2014)
Ion transporters in brain endothelial cells that contribute to formation of brain interstitial fluid
Ruth Mokgokong et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2014)
Urokinase-Type Plasminogen Activator Receptor Modulates Epileptogenesis in Mouse Model of Temporal Lobe Epilepsy
Xavier Ekolle Ndode-Ekane et al.
MOLECULAR NEUROBIOLOGY (2013)
Cation-chloride cotransporters NKCC1 and KCC2 as potential targets for novel antiepileptic and antiepileptogenic treatments
Wolfgang Loescher et al.
NEUROPHARMACOLOGY (2013)
Correction: Bumetanide Enhances Phenobarbital Efficacy in a Rat Model of Hypoxic Neonatal Seizures
Ryan T. Cleary et al.
PLoS One (2013)
A Causative Link Between Inner Ear Defects and Long-Term Striatal Dysfunction
Michelle W. Antoine et al.
SCIENCE (2013)
The extracellular space and epileptic activity in the adult brain: Explaining the antiepileptic effects of furosemide and bumetanide
Daryl W. Hochman
EPILEPSIA (2012)
New insights into the role of hilar ectopic granule cells in the dentate gyrus based on quantitative anatomic analysis and three-dimensional reconstruction
Helen E. Scharfman et al.
EPILEPSIA (2012)
GABAergic excitation after febrile seizures induces ectopic granule cells and adult epilepsy
Ryuta Koyama et al.
NATURE MEDICINE (2012)
The GABA Excitatory/Inhibitory Shift in Brain Maturation and Neurological Disorders
Yehezkel Ben-Ari et al.
NEUROSCIENTIST (2012)
Ischemia-induced stimulation of Na-K-Cl cotransport in cerebral microvascular endothelial cells involves AMP kinase
Breanna K. Wallace et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2011)
Positive shifts of the GABAA receptor reversal potential due to altered chloride homeostasis is widespread after status epilepticus
Gleb Barmashenko et al.
EPILEPSIA (2011)
Increase in BDNF-mediated TrkB signaling promotes epileptogenesis in a mouse model of mesial temporal lobe epilepsy
Christophe Heinrich et al.
NEUROBIOLOGY OF DISEASE (2011)
Interleukin-1β Biosynthesis Inhibition Reduces Acute Seizures and Drug Resistant Chronic Epileptic Activity in Mice
Mattia Maroso et al.
NEUROTHERAPEUTICS (2011)
Disease-Modifying Effects of Phenobarbital and the NKCC1 Inhibitor Bumetanide in the Pilocarpine Model of Temporal Lobe Epilepsy
Claudia Brandt et al.
JOURNAL OF NEUROSCIENCE (2010)
Molecular mechanisms of microvascular failure in central nervous system injury-synergistic roles of NKCC1 and SUR1/TRPM4 A review
J. Marc Simard et al.
JOURNAL OF NEUROSURGERY (2010)
Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research
Carol Kilkenny et al.
PLOS BIOLOGY (2010)
Bumetanide for neonatal seizures: Based on evidence or enthusiasm?
Sampsa Vanhatalo et al.
EPILEPSIA (2009)
Differences in sensitivity to the convulsant pilocarpine in substrains and sublines of C57BL/6 mice
C. J. Mueller et al.
GENES BRAIN AND BEHAVIOR (2009)
Bumetanide, an NKCC1 Antagonist, Does Not Prevent Formation of Epileptogenic Focus but Blocks Epileptic Focus Seizures in Immature Rat Hippocampus
Romain Nardou et al.
JOURNAL OF NEUROPHYSIOLOGY (2009)
Compensatory Enhancement of Intrinsic Spiking upon NKCC1 Disruption in Neonatal Hippocampus
Sampsa T. Sipila et al.
JOURNAL OF NEUROSCIENCE (2009)
Cation-Chloride Cotransporters and Neuronal Function
Peter Blaesse et al.
NEURON (2009)
Long-term expressional changes of Na+-K+-Cl- co-transporter 1 (NKCC1) and K+-Cl- co-transporter 2 (KCC2) in CA1 region of hippocampus following lithium-pilocarpine induced status epilepticus (PISE)
Xiubin Li et al.
BRAIN RESEARCH (2008)
NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus
Lei Zhu et al.
EPILEPSY RESEARCH (2008)
Is my antibody-staining specific? How to deal with pitfalls of immunohistochemistry
Jean-Marc Fritschy
EUROPEAN JOURNAL OF NEUROSCIENCE (2008)
Behavioral alterations in a mouse model of temporal lobe epilepsy induced by intrahippocampal injection of kainate
Ina Groeticke et al.
EXPERIMENTAL NEUROLOGY (2008)
Analyzing real-time PCR data by the comparative C-T method
Thomas D. Schmittgen et al.
NATURE PROTOCOLS (2008)
The bumetanide-sensitive Na-K-2Cl cotransporter NKCC1 as a potential target of a novel mechanism-based treatment strategy for neonatal seizures
Kristopher T. Kahle et al.
NEUROSURGICAL FOCUS (2008)
Roles of the cation-chloride cotransporters in neurological disease
Kristopher T. Kahle et al.
NATURE CLINICAL PRACTICE NEUROLOGY (2008)
Disrupted dentate granule cell chloride regulation enhances synaptic excitability during development of temporal lobe epilepsy
Hemal R. Pathak et al.
JOURNAL OF NEUROSCIENCE (2007)
Perturbed chloride homeostasis and GABAergic signaling in human temporal lobe epilepsy
Gilles Huberfeld et al.
JOURNAL OF NEUROSCIENCE (2007)
Cation-chloride cotransporters and GABA-ergic innervation in the human epileptic hippocampus
Alberto Munoz et al.
EPILEPSIA (2007)
Stereological methods reveal the robust size and stability of ectopic hilar granule cells after pilocarpine-induced status epilepticus in the adult rat
Daniel P. McCloskey et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2006)
Epilepsy induced by extended amygdala-kindling in rats:: lack of clear association between development of spontaneous seizures and neuronal damage
C Brandt et al.
EPILEPSY RESEARCH (2004)
Changes in chloride homeostasis-regulating gene expressions in the rat hippocampus following amygdala kindling
A Okabe et al.
BRAIN RESEARCH (2003)
Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model
K Borges et al.
EXPERIMENTAL NEUROLOGY (2003)
BDNF-induced TrkB activation down-regulates the K+-Cl- cotransporter KCC2 and impairs neuronal Cl- extrusion
C Rivera et al.
JOURNAL OF CELL BIOLOGY (2002)
On the origin of interictal activity in human temporal lobe epilepsy in vitro
I Cohen et al.
SCIENCE (2002)
Evolution of hippocampal epileptic activity during the development of hippocampal sclerosis in a mouse model of temporal lobe epilepsy
V Riban et al.
NEUROSCIENCE (2002)