4.8 Review

Unconventional viral gene expression mechanisms as therapeutic targets

Related references

Note: Only part of the references are listed.
Article Biochemical Research Methods

VirusCircBase: a database of virus circular RNAs

Zena Cai et al.

Summary: A systematic survey identified numerous viral circRNAs from 23 viral species, including both double-stranded DNA viruses and single-stranded RNA viruses. These viral circRNAs exhibit diverse characteristics and are involved in various cellular activities and diseases.

BRIEFINGS IN BIOINFORMATICS (2021)

Article Multidisciplinary Sciences

The coding capacity of SARS-CoV-2

Yaara Finkel et al.

Summary: A high-resolution map of coding regions in the SARS-CoV-2 genome enables the identification of 23 unannotated open reading frames and quantification of the expression of canonical viral open reading frames.

NATURE (2021)

Article Biochemistry & Molecular Biology

The Architecture of SARS-CoV-2 Transcriptome

Dongwan Kim et al.

Article Multidisciplinary Sciences

Proteomics of SARS-CoV-2-infected host cells reveals therapy targets

Denisa Bojkova et al.

NATURE (2020)

Article Multidisciplinary Sciences

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

David E. Gordon et al.

NATURE (2020)

Article Biochemistry & Molecular Biology

Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection

Jessica Sook Yuin Ho et al.

Article Genetics & Heredity

IRESbase: A Comprehensive Database of Experimentally Validated Internal Ribosome Entry Sites

Jian Zhao et al.

GENOMICS PROTEOMICS & BIOINFORMATICS (2020)

Article Virology

Properties and abundance of overlapping genes in viruses

Timothy E. Schlub et al.

VIRUS EVOLUTION (2020)

Article Multidisciplinary Sciences

Direct RNA sequencing on nanopore arrays redefines the transcriptional complexity of a viral pathogen

Daniel P. Depledge et al.

NATURE COMMUNICATIONS (2019)

Article Microbiology

Comprehensive profiling of translation initiation in influenza virus infected cells

Heather M. Machkovech et al.

PLOS PATHOGENS (2019)

Review Biochemistry & Molecular Biology

Exploitation of glycosylation in enveloped virus pathobiology

Yasunori Watanabe et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2019)

Review Infectious Diseases

Influenza virus polymerase inhibitors in clinical development

Frederick G. Hayden et al.

CURRENT OPINION IN INFECTIOUS DISEASES (2019)

Article Virology

Zika Virus Subverts Stress Granules To Promote and Restrict Viral Gene Expression

Gaston Bonenfant et al.

JOURNAL OF VIROLOGY (2019)

Review Cell Biology

Viral modulation of cellular RNA alternative splicing: A new key player in virus-host interactions?

Simon Boudreault et al.

WILEY INTERDISCIPLINARY REVIEWS-RNA (2019)

Article Multidisciplinary Sciences

Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus

Jiawei Zhao et al.

NATURE COMMUNICATIONS (2019)

Article Pharmacology & Pharmacy

Regulation of influenza A virus mRNA splicing by CLK1

Anita Artarini et al.

ANTIVIRAL RESEARCH (2019)

Review Immunology

CAR T Cells Beyond Cancer: Hope for Immunomodulatory Therapy of Infectious Diseases

Michelle Seif et al.

FRONTIERS IN IMMUNOLOGY (2019)

Review Microbiology

Prisoners of war - host adaptation and its constraints on virus evolution

Peter Simmonds et al.

NATURE REVIEWS MICROBIOLOGY (2019)

Article Multidisciplinary Sciences

The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant

Boris Bogdanow et al.

NATURE COMMUNICATIONS (2019)

Article Immunology

Susceptibility of Influenza A, B, and D Viruses to Baloxavir

Vasiliy P. Mishin et al.

EMERGING INFECTIOUS DISEASES (2019)

Review Biochemistry & Molecular Biology

Therapeutic Applications of Targeted Alternative Splicing to Cancer Treatment

Jung-Chun Lin

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Immunology

Influenza Virus: Dealing with a Drifting and Shifting Pathogen

Hyunsuh Kim et al.

VIRAL IMMUNOLOGY (2018)

Article Medicine, General & Internal

Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques

Jeremie Guedj et al.

PLOS MEDICINE (2018)

Article Multidisciplinary Sciences

Ancient hepatitis B viruses from the Bronze Age to the Medieval period

Barbara Muhlemann et al.

NATURE (2018)

Article Biochemistry & Molecular Biology

Influenza virus infection causes global RNAPII termination defects

Nan Zhao et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)

Article Multidisciplinary Sciences

Expanded subgenomic mRNA transcriptome and coding capacity of a nidovirus

Han Di et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Review Oncology

Combination therapy in combating cancer

Reza Bayat Mokhtari et al.

ONCOTARGET (2017)

Article Genetics & Heredity

Origin and Evolution of RNA-Dependent RNA Polymerase

Savio T. de Farias et al.

FRONTIERS IN GENETICS (2017)

Review Biochemistry & Molecular Biology

Upstream Open Reading Frames Differentially Regulate Gene-specific Translation in the Integrated Stress Response

Sara K. Young et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2016)

Article Biochemistry & Molecular Biology

RNA-binding protein CPEB1 remodels host and viral RNA landscapes

Ranjan Batra et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)

Article Biochemistry & Molecular Biology

RNA-binding protein CPEB1 remodels host and viral RNA landscapes

Ranjan Batra et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)

Review Genetics & Heredity

Functional Translational Readthrough: A Systems Biology Perspective

Fabian Schueren et al.

PLOS GENETICS (2016)

Article Biochemistry & Molecular Biology

Molecular architecture of the ribosome-bound Hepatitis C Virus internal ribosomal entry site RNA

Hiroshi Yamamoto et al.

EMBO JOURNAL (2015)

Article Biochemistry & Molecular Biology

Transcriptional slippage in the positive-sense RNA virus family Potyviridae

Allan Olspert et al.

EMBO REPORTS (2015)

Article Immunology

Enhanced Recognition of HIV-1 Cryptic Epitopes Restricted by HLA Class I Alleles Associated With a Favorable Clinical Outcome

Anju Bansal et al.

JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES (2015)

Article Biochemistry & Molecular Biology

Influenza A virus preferentially snatches noncoding RNA caps

Weifeng Gu et al.

Article Virology

Continuous and Discontinuous RNA Synthesis in Coronaviruses

Isabel Sola et al.

ANNUAL REVIEW OF VIROLOGY, VOL 2 (2015)

Article Biochemistry & Molecular Biology

Initiation of Translation by Cricket Paralysis Virus IRES Requires Its Translocation in the Ribosome

Israel S. Fernandez et al.

Article Biochemistry & Molecular Biology

RACK1 Controls IRES-Mediated Translation of Viruses

Karim Majzoub et al.

Article Biochemistry & Molecular Biology

The mechanism of translation initiation on Type 1 picornavirus IRESs

Trevor R. Sweeney et al.

EMBO JOURNAL (2014)

Article Immunology

Characterization of T-Cell Responses to Cryptic Epitopes in Recipients of a Noncodon-Optimized HIV-1 Vaccine

Anne Bet et al.

JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES (2014)

Article Chemistry, Multidisciplinary

Anti-frameshifting Ligand Reduces the Conformational Plasticity of the SARS Virus Pseudoknot

Dustin B. Ritchie et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

Article Multidisciplinary Sciences

Structural insight into cap-snatching and RNA synthesis by influenza polymerase

Stefan Reich et al.

NATURE (2014)

Review Multidisciplinary Sciences

Emerging Principles for the Therapeutic Exploitation of Glycosylation

Martin Dalziel et al.

SCIENCE (2014)

Article Biotechnology & Applied Microbiology

Phylogenetic patterns of emergence of new genes support a model of frequent de novo evolution

Rafik Neme et al.

BMC GENOMICS (2013)

Review Biotechnology & Applied Microbiology

Combination approaches to combat multidrug-resistant bacteria

Roberta J. Worthington et al.

TRENDS IN BIOTECHNOLOGY (2013)

Article Biochemistry & Molecular Biology

Observation of dually decoded regions of the human genome using ribosome profiling data

Audrey M. Michel et al.

GENOME RESEARCH (2012)

Review Biotechnology & Applied Microbiology

Non-canonical translation in RNA viruses

Andrew E. Firth et al.

JOURNAL OF GENERAL VIROLOGY (2012)

Review Microbiology

Conventional and unconventional mechanisms for capping viral mRNA

Etienne Decroly et al.

NATURE REVIEWS MICROBIOLOGY (2012)

Article Biochemistry & Molecular Biology

2A peptides provide distinct solutions to driving stop-carry on translational recoding

Pamila Sharma et al.

NUCLEIC ACIDS RESEARCH (2012)

Article Multidisciplinary Sciences

Structure of a hepatitis C virus RNA domain in complex with a translation inhibitor reveals a binding mode reminiscent of riboswitches

Sergey M. Dibrov et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Multidisciplinary Sciences

Programmed-1 frameshifting efficiency correlates with RNA pseudoknot conformational plasticity, not resistance to mechanical unfolding

Dustin B. Ritchie et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Medicine, Research & Experimental

HIV-1 Antiretroviral Drug Therapy

Eric J. Arts et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)

Review Cell Biology

Mechanisms and implications of programmed translational frameshifting

Jonathan D. Dinman

WILEY INTERDISCIPLINARY REVIEWS-RNA (2012)

Article Virology

A New Ebola Virus Nonstructural Glycoprotein Expressed through RNA Editing

Masfique Mehedi et al.

JOURNAL OF VIROLOGY (2011)

Article Biochemistry & Molecular Biology

Overlapping signals for translational regulation and packaging of influenza A virus segment 2

Helen M. Wise et al.

NUCLEIC ACIDS RESEARCH (2011)

Article Multidisciplinary Sciences

Ribosomal frameshifting into an overlapping gene in the 2B-encoding region of the cardiovirus genome

Gary Loughran et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Virology

The genome-linked protein VPg of vertebrate viruses - a multifaceted protein

Ian Goodfellow

CURRENT OPINION IN VIROLOGY (2011)

Article Biotechnology & Applied Microbiology

The N-terminus of Bunyamwera orthobunyavirus NSs protein is essential for interferon antagonism

Ingeborg van Knippenberg et al.

JOURNAL OF GENERAL VIROLOGY (2010)

Article Immunology

Robust, Vaccine-Induced CD8(+) T Lymphocyte Response against an Out-of-Frame Epitope

Nicholas J. Maness et al.

JOURNAL OF IMMUNOLOGY (2010)

Article Biochemistry & Molecular Biology

Conformational inhibition of the hepatitis C virus internal ribosome entry site RNA

Jerod Parsons et al.

NATURE CHEMICAL BIOLOGY (2009)

Article Multidisciplinary Sciences

Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans

Sarah E. Calvo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Biochemistry & Molecular Biology

Translation initiation factors are not required for Dicistroviridae IRES function in vivo

Nilsa Deniz et al.

Article Biotechnology & Applied Microbiology

Occurrence, function and evolutionary origins of '2A-like' sequences in virus genomes

Garry A. Luke et al.

JOURNAL OF GENERAL VIROLOGY (2008)

Article Biotechnology & Applied Microbiology

Transcriptional slippage prompts recoding in alternate reading frames in the hepatitis C virus (HCV) core sequence from strain HCV-1

Maxime Ratinier et al.

JOURNAL OF GENERAL VIROLOGY (2008)

Review Biochemistry & Molecular Biology

Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides

Rudy Juliano et al.

NUCLEIC ACIDS RESEARCH (2008)

Article Biochemical Research Methods

A first look at ARFome: Dual-coding genes in mammalian Genomes

Wen-Yu Chung et al.

PLOS COMPUTATIONAL BIOLOGY (2007)

Article Biotechnology & Applied Microbiology

Prevalence of PB1-F2 of influenza A viruses

Roland Zell et al.

JOURNAL OF GENERAL VIROLOGY (2007)

Article Biochemistry & Molecular Biology

Unconventional mechanism of mRNA capping by the RNA-dependent RNA polymerase of vesicular stomatitis virus

Tomoaki Ogino et al.

MOLECULAR CELL (2007)

Review Microbiology

Timeline -: The Tombusvirus-encoded P19:: from irrelevance to elegance

HB Scholthof

NATURE REVIEWS MICROBIOLOGY (2006)

Article Biochemical Research Methods

Detecting overlapping coding sequences in virus genomes

AE Firth et al.

BMC BIOINFORMATICS (2006)

Article Multidisciplinary Sciences

An unusual internal ribosome entry site in the herpes simplex virus thymidine kinase gene

A Griffiths et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Review Biotechnology & Applied Microbiology

Paramyxovirus mRNA editing, the 'rule of six' and error catastrophe: a hypothesis

D Kolakofsky et al.

JOURNAL OF GENERAL VIROLOGY (2005)

Article Biochemistry & Molecular Biology

Coupled translation of the respiratory syncytial virus M2 open reading frames requires upstream sequences

PS Gould et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemical Research Methods

Detecting overlapping coding sequences with pairwise alignments

AE Firth et al.

BIOINFORMATICS (2005)

Article Biochemistry & Molecular Biology

The two upstream open reading frames of oncogene mdm2 have different translational regulatory properties

XP Jin et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

A novel influenza A virus mitochondrial protein that induces cell death

WS Chen et al.

NATURE MEDICINE (2001)

Article Virology

Rule of six:: How does the Sendai virus RNA polymerase keep count?

D Vulliémoz et al.

JOURNAL OF VIROLOGY (2001)

Article Biochemistry & Molecular Biology

Naturally occurring dicistronic cricket paralysis virus RNA is regulated by two internal ribosome entry sites

JE Wilson et al.

MOLECULAR AND CELLULAR BIOLOGY (2000)

Article Multidisciplinary Sciences

Methionine-independent initiation of translation in the capsid protein of an insect RNA virus

J Sasaki et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)