Chemical constituents from Lactuca plumieri (L.) Gren. & Godr. (Asteraceae)

This is the first report concerning the natural products of the hitherto unstudied Lactuca plumieri (L.) Gren. & Godr., a member of the tribe Cichorieae (Asteraceae). From aerial parts and roots of this plant, five sesquiterpene lactones and one coumarin were isolated. The compounds were identified as sonchuside A, 11 beta,13-dihydrolactucin-8-O-acetate, 11 beta,13-dihydrolactucin, cichorioside B, 11 beta,13-dihydrolactucin-8-O-acetate-15-O-beta-glucopyranoside and coumarin - cichoriin. Their structures were established by H-1 NMR. Moreover, HPLC/PAD analysis of a hydroalcoholic extract from the aerial parts of the plant revealed the presence of caffeic acid derivatives, coumarins and flavonoids commonly found in lettuces. [GRAPHICS] .

Automated summary

This report presents the first study on the natural products of the previously unstudied Lactuca plumieri, identifying five sesquiterpene lactones and one coumarin. Additionally, analysis showed the presence of caffeic acid derivatives, coumarins, and flavonoids in the aerial parts of the plant.